An Integrative Transcriptomic Analysis for Identifying Novel Target Genes Corresponding to Severity Spectrum in Spinal Muscular Atrophy

Expression of TNF-α, VEGF, and MMP-3 mRNAs in synovial tissues and their roles in fibroblast-mediated osteogenesis in ankylosing spondylitis

(2015) K.G. Liu et al.   GENETICS AND MOLECULAR RESEARCH

GAPDH and β-actin protein decreases with aging, making Stain-Free technology a superior loading control in Western blotting of human skeletal muscle

(2015) Andreas Vigelsø et al.   JOURNAL OF APPLIED PHYSIOLOGY

Spinal muscular atrophy—recent therapeutic advances for an old challenge

(2015) Irene Faravelli et al.   Nature Reviews Neurology

Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse

(2015) Vicki L. McGovern et al.   PLoS One

Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis

(2015) Hanadie Yousef et al.   STEM CELLS

Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: Evidence for involvement of splicing regulatory proteins

(2015) Qing Huo et al.   RNA Biology

DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy

(2014) Caroline A. Garrett et al.   BRAIN

From cytokine to myokine: the emerging role of interleukin-6 in metabolic regulation

(2014) Martin Pal et al.   IMMUNOLOGY AND CELL BIOLOGY

Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

(2014) Thomas M. Wishart et al.   JOURNAL OF CLINICAL INVESTIGATION

Systemic Administration of a Recombinant AAV1 Vector Encoding IGF-1 Improves Disease Manifestations in SMA Mice

(2014) Li-Kai Tsai et al.   MOLECULAR THERAPY

Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target

(2014) Rachael A. Powis et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Transcriptome Profiling of Spinal Muscular Atrophy Motor Neurons Derived from Mouse Embryonic Stem Cells

(2014) Miho Maeda et al.   PLoS One

Plasminogen Activator Inhibitor-1 in Aging

(2014) Kyosuke Takeshita et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Endocrine Crosstalk Between Muscle and Bone

(2014) Marco Brotto et al.   Current Osteoporosis Reports

How genetic modifiers influence the phenotype of spinal muscular atrophy and suggest future therapeutic approaches

(2013) Brunhilde Wirth et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Contactins in the neurobiology of autism

(2013) Amila Zuko et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy

(2013) Kelvin See et al.   HUMAN MOLECULAR GENETICS

Spinal muscular atrophy: a motor neuron disorder or a multi-organ disease?

(2013) Monir Shababi et al.   JOURNAL OF ANATOMY

An old method facing a new challenge: Re-visiting housekeeping proteins as internal reference control for neuroscience research

(2013) Rena Li et al.   LIFE SCIENCES

When Is Hub Gene Selection Better than Standard Meta-Analysis?

(2013) Peter Langfelder et al.   PLoS One

Selective Vulnerability of Spinal and Cortical Motor Neuron Subpopulations in delta7 SMA Mice

(2013) Paolo d’Errico et al.   PLoS One

SMN Is Required for Sensory-Motor Circuit Function in Drosophila

(2012) Wendy L. Imlach et al.   CELL

Modification of phenotype by SMN2 copy numbers in two Chinese families with SMN1 deletion in two continuous generations

(2012) Wan-Jin Chen et al.   CLINICA CHIMICA ACTA

The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy

(2012) Saif Ahmad et al.   HUMAN MOLECULAR GENETICS

Interleukin-6, a Major Cytokine in the Central Nervous System

(2012) María Erta et al.   International Journal of Biological Sciences

Human Axonal Survival of Motor Neuron (a-SMN) Protein Stimulates Axon Growth, Cell Motility, C-C Motif Ligand 2 (CCL2), and Insulin-like Growth Factor-1 (IGF1) Production

(2012) Denise Locatelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expanding the Ig Superfamily Code for Laminar Specificity in Retina: Expression and Role of Contactins

(2012) M. Yamagata et al.   JOURNAL OF NEUROSCIENCE

Call in the backup

(2012) Elie Dolgin   NATURE MEDICINE

Cytokine dysregulation in autism spectrum disorders (ASD): Possible role of the environment

(2012) Paula E. Goines et al.   NEUROTOXICOLOGY AND TERATOLOGY

Genetic Correction of Human Induced Pluripotent Stem Cells from Patients with Spinal Muscular Atrophy

(2012) S. Corti et al.   Science Translational Medicine

Spinal muscular atrophy: going beyond the motor neuron

(2012) Gillian Hamilton et al.   TRENDS IN MOLECULAR MEDICINE

Maternal xNorrin, a Canonical Wnt Signaling Agonist and TGF-β Antagonist, Controls Early Neuroectoderm Specification in Xenopus

(2012) Suhong Xu et al.   PLOS BIOLOGY

Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III

(2011) Galina Yu Zheleznyakova et al.   BMC Medical Genetics

Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway

(2011) Faraz Farooq et al.   JOURNAL OF CLINICAL INVESTIGATION

IGF-1 delivery to CNS attenuates motor neuron cell death but does not improve motor function in type III SMA mice

(2011) Li-Kai Tsai et al.   NEUROBIOLOGY OF DISEASE

Early Functional Impairment of Sensory-Motor Connectivity in a Mouse Model of Spinal Muscular Atrophy

(2011) George Z. Mentis et al.   NEURON

A Spontaneous Mutation in Contactin 1 in the Mouse

(2011) Muriel T. Davisson et al.   PLoS One

Overexpression of Bcl2 in Osteoblasts Inhibits Osteoblast Differentiation and Induces Osteocyte Apoptosis

(2011) Takeshi Moriishi et al.   PLoS One

Newborn and carrier screening for spinal muscular atrophy

(2010) Thomas W. Prior et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy

(2010) Kaiguo Mo et al.   PLoS One

Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways

(2010) Jeremy A. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coexistence of an unbalanced chromosomal rearrangement and spinal muscular atrophy in an infant with multiple congenital anomalies

(2009) Shay Ben-Shachar et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Different atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy

(2009) Caterina Millino et al.   BMC Medicine

Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?

(2009) Arthur H. M. Burghes et al.   NATURE REVIEWS NEUROSCIENCE

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

An autopsy case of spinal muscular atrophy type III (Kugelberg-Welander disease)

(2008) Satoshi Kuru et al.   NEUROPATHOLOGY

Plastin 3 Is a Protective Modifier of Autosomal Recessive Spinal Muscular Atrophy

(2008) G. E. Oprea et al.   SCIENCE