CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis

An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation

(2015) Mingjiazi Chen et al.   PLoS One

γδT Cells: First Line of Defense and Beyond

(2014) Yueh-hsiu Chien et al.   Annual Review of Immunology

Ecto-5′-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature

(2014) Gennady G. Yegutkin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Only a Subset of Phosphoantigen-Responsive  9 2 T Cells Mediate Protective Tuberculosis Immunity

(2014) C. T. Spencer et al.   JOURNAL OF IMMUNOLOGY

Anti-Inflammatory or Proinflammatory Effect of an Adenosine Receptor Agonist on the Th17 Autoimmune Response Is Inflammatory Environment–Dependent

(2014) Dongchun Liang et al.   JOURNAL OF IMMUNOLOGY

Nucleotide signalling during inflammation

(2014) Marco Idzko et al.   NATURE

CD73 Expression Is Dynamically Regulated in the Germinal Center and Bone Marrow Plasma Cells Are Diminished in Its Absence

(2014) Laura J. Conter et al.   PLoS One

Roles of the Adenosine Receptor and CD73 in the Regulatory Effect of γδ T Cells

(2014) Dongchun Liang et al.   PLoS One

The Co-Stimulatory Effects of MyD88-Dependent Toll-Like Receptor Signaling on Activation of Murine γδ T Cells

(2014) Jinping Zhang et al.   PLoS One

γδ T cells for cancer immunotherapy

(2014) Jonathan PH Fisher et al.   OncoImmunology

CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+T cells contributes to their regulatory function

(2013) Lesley Ann Smyth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD73+ regulatory T cells contribute to adenosine-mediated resolution of acute lung injury

(2013) Heidi Ehrentraut et al.   FASEB JOURNAL

IL-23 Receptor Expression on    T Cells Correlates with Their Enhancing or Suppressive Effects on Autoreactive T Cells in Experimental Autoimmune Uveitis

(2013) D. Liang et al.   JOURNAL OF IMMUNOLOGY

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

Role of CD25+ Dendritic Cells in the Generation of Th17 Autoreactive T Cells in Autoimmune Experimental Uveitis

(2012) D. Liang et al.   JOURNAL OF IMMUNOLOGY

In vivo priming of IL-17+ uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via γδ T cell activation

(2012) Aijun Zuo et al.   MOLECULAR IMMUNOLOGY

Resident Cardiac Immune Cells and Expression of the Ectonucleotidase Enzymes CD39 and CD73 after Ischemic Injury

(2012) Florian Bönner et al.   PLoS One

CD73: a potent suppressor of antitumor immune responses

(2012) Paul. A. Beavis et al.   TRENDS IN IMMUNOLOGY

Autoimmune Dysregulation and Purine Metabolism in Adenosine Deaminase Deficiency

(2012) Aisha Vanessa Sauer et al.   Frontiers in Immunology

Extracellular purine metabolism and signaling of CD73-derived adenosine in murine Treg and Teff cells

(2011) Michael Romio et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis

(2011) J. Stagg et al.   CANCER RESEARCH

CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice

(2011) Long Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors

(2011) U. Schenk et al.   Science Signaling

γδ T-cell immunotherapy for lung cancer

(2011) Yukihiro Yoshida et al.   SURGERY TODAY

CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression

(2010) D. Jin et al.   CANCER RESEARCH

Targeting    T Lymphocytes for Cancer Immunotherapy: From Novel Mechanistic Insight to Clinical Application

(2010) A. Q. Gomes et al.   CANCER RESEARCH

γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism

(2010) Franziska Petermann et al.   IMMUNITY

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

(2010) John R. Grainger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

(2010) J. Stagg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Major Role of    T Cells in the Generation of IL-17+ Uveitogenic T Cells

(2009) Y. Cui et al.   JOURNAL OF IMMUNOLOGY

Purinergic signaling and immune modulation at the schistosome surface?

(2009) Rita Bhardwaj et al.   TRENDS IN PARASITOLOGY

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

(2008) Gennady G. Yegutkin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY

CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis

(2008) J. H. Mills et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1  and IL-18 secretion in an autocrine way

(2008) A. Piccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA