Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event

Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR)

(2015) Keiyu Oshida et al.   TOXICOLOGY

Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

(2015) Keiyu Oshida et al.   PLoS One

Genetic background determines ifStat5bsuppresses or enhances murine hepatocarcinogenesis

(2014) Christopher C. Oberley et al.   MOLECULAR CARCINOGENESIS

Minireview: Mechanisms of Growth Hormone-Mediated Gene Regulation

(2014) Dennis J. Chia   MOLECULAR ENDOCRINOLOGY

Dose-Response Modeling of Early Molecular and Cellular Key Events in the CAR-Mediated Hepatocarcinogenesis Pathway

(2014) David R. Geter et al.   TOXICOLOGICAL SCIENCES

Regulation of STAT signaling by acetylation

(2013) Shougang Zhuang   CELLULAR SIGNALLING

Genotype-Dependent Effects of TGF- 1 on Mast Cell Function: Targeting the Stat5 Pathway

(2013) J. Fernando et al.   JOURNAL OF IMMUNOLOGY

Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice

(2013) Yanjun Jiang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Aryl hydrocarbon receptor-dependence of dioxin’s effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components

(2012) Chunja Lee et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Caveolin-1 plays a critical role in host immunity against Klebsiella pneumoniae by regulating STAT5 and Akt activity

(2012) Qiang Guo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Healthy Aging: Is Smaller Better? – A Mini-Review

(2012) Andrzej Bartke   GERONTOLOGY

Growth hormone STAT5-mediated signaling and its modulation in mice liver during the growth period

(2012) Carolina S. Martinez et al.   GROWTH HORMONE & IGF RESEARCH

Orphan Nuclear Receptor Small Heterodimer Partner Negatively Regulates Growth Hormone-mediated Induction of Hepatic Gluconeogenesis through Inhibition of Signal Transducer and Activator of Transcription 5 (STAT5) Transactivation

(2012) Yong Deuk Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of CUX2 on the Female Mouse Liver Transcriptome: Activation of Female-Biased Genes and Repression of Male-Biased Genes

(2012) T. L. Conforto et al.   MOLECULAR AND CELLULAR BIOLOGY

Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development

(2012) Kristina M. Mueller et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

(2012) Yuan Zhang et al.   eLife

Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood

(2012) Tara L Conforto et al.   Biology of Sex Differences

Development of a Method for the Determination of Pulsatile Growth Hormone Secretion in Mice

(2011) F. J. Steyn et al.   ENDOCRINOLOGY

Dynamic, Sex-Differential STAT5 and BCL6 Binding to Sex-Biased, Growth Hormone-Regulated Genes in Adult Mouse Liver

(2011) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Hepatic Xenobiotic Metabolizing Enzyme and Transporter Gene Expression through the Life Stages of the Mouse

(2011) Janice S. Lee et al.   PLoS One

Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor

(2010) Raoul Frijters et al.   BMC GENOMICS

4β-hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans

(2010) Ulf Diczfalusy et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Nuclear Orphan Receptor TAK1/TR4-Deficient Mice Are Protected Against Obesity-Linked Inflammation, Hepatic Steatosis, and Insulin Resistance

(2010) H. S. Kang et al.   DIABETES

The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression

(2010) Ji Hoon Yu et al.   HEPATOLOGY

MicroRNAs Regulate Pituitary Development, and MicroRNA 26b Specifically Targets Lymphoid Enhancer Factor 1 (Lef-1), Which Modulates Pituitary Transcription Factor 1 (Pit-1) Expression

(2010) Zichao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unbiased, Genome-Wide In Vivo Mapping of Transcriptional Regulatory Elements Reveals Sex Differences in Chromatin Structure Associated with Sex-Specific Liver Gene Expression

(2010) G. Ling et al.   MOLECULAR AND CELLULAR BIOLOGY

Sex-Related Differences in Gene Expression Following Coxiella burnetii Infection in Mice: Potential Role of Circadian Rhythm

(2010) Julien Textoris et al.   PLoS One

Ontology-Based Meta-Analysis of Global Collections of High-Throughput Public Data

(2010) Ilya Kupershmidt et al.   PLoS One

Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice

(2009) Kai Sun et al.   HEPATOLOGY

In VivoTargeting of the Growth Hormone Receptor (GHR) Box1 Sequence Demonstrates that the GHR Does Not Signal Exclusively through JAK2

(2009) Johanna L. Barclay et al.   MOLECULAR ENDOCRINOLOGY

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

(2009) D. J. Waxman et al.   MOLECULAR PHARMACOLOGY

Inhibition of Growth Hormone Signaling by the Fasting-Induced Hormone FGF21

(2008) Takeshi Inagaki et al.   Cell Metabolism

Hepatic function is preserved in the absence of mature microRNAs

(2008) Nicholas J. Hand et al.   HEPATOLOGY

Liver-Specific Hepatocyte Nuclear Factor-4α Deficiency: Greater Impact on Gene Expression in Male than in Female Mouse Liver

(2008) Minita G. Holloway et al.   MOLECULAR ENDOCRINOLOGY

Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms

(2008) Björn Schumacher et al.   PLoS Genetics

How growth hormone controls growth, obesity and sexual dimorphism

(2007) Agnieszka M. Lichanska et al.   TRENDS IN GENETICS