Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium
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Title
Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium
Authors
Keywords
Gene expression, Gene regulation, Fatty liver, Mice, Fatty acids, Steatosis, Hepatocytes, Transcription factors
Journal
PLoS One
Volume 10, Issue 2, Pages e0112655
Publisher
Public Library of Science (PLoS)
Online
2015-02-18
DOI
10.1371/journal.pone.0112655
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- (2012) Mirjam M. Schaap et al. ARCHIVES OF TOXICOLOGY
- The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism
- (2012) Mary C. Hunt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2012) Tsutomu Matsubara et al. Cell Metabolism
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- (2011) Anne Tailleux et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
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- (2010) Cristi L. Galindo et al. COMPARATIVE AND FUNCTIONAL GENOMICS
- Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
- (2010) Gerald T. Ankley et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
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- (2009) H.-H. Liu et al. GENOME RESEARCH
- Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine
- (2009) Ann M. Thomas et al. HEPATOLOGY
- Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species
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- Gene expression profiling in the liver and lung of perfluorooctane sulfonate-exposed mouse fetuses: Comparison to changes induced by exposure to perfluorooctanoic acid
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- Coexposure of Mice to Trovafloxacin and Lipopolysaccharide, a Model of Idiosyncratic Hepatotoxicity, Results in a Unique Gene Expression Profile and Interferon Gamma–Dependent Liver Injury
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