Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1
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Title
Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1
Authors
Keywords
Mitochondria, Breast cancer, Cell metabolism, Cell cycle and cell division, Glycolysis, Oxidation, Drug metabolism, Transcription factors
Journal
PLoS One
Volume 11, Issue 2, Pages e0150232
Publisher
Public Library of Science (PLoS)
Online
2016-02-27
DOI
10.1371/journal.pone.0150232
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