A Novel High Content Imaging-Based Screen Identifies the Anti-Helminthic Niclosamide as an Inhibitor of Lysosome Anterograde Trafficking and Prostate Cancer Cell Invasion
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Title
A Novel High Content Imaging-Based Screen Identifies the Anti-Helminthic Niclosamide as an Inhibitor of Lysosome Anterograde Trafficking and Prostate Cancer Cell Invasion
Authors
Keywords
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Journal
PLoS One
Volume 11, Issue 1, Pages e0146931
Publisher
Public Library of Science (PLoS)
Online
2016-01-20
DOI
10.1371/journal.pone.0146931
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Note: Only part of the references are listed.- LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells
- (2015) Peidu Jiang et al. METHODS
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- (2013) R. Li et al. MOLECULAR CANCER THERAPEUTICS
- Disruption of STAT3 by Niclosamide Reverses Radioresistance of Human Lung Cancer
- (2013) S. You et al. MOLECULAR CANCER THERAPEUTICS
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- (2013) Yu-Chi Wang et al. PLoS One
- The HGF-Met Signaling Axis: Emerging Themes and Targets of Inhibition
- (2012) David T. Coleman et al. CURRENT PROTEIN & PEPTIDE SCIENCE
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- (2012) De-Qin Yang et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2012) Mahadeo A. Sukhai et al. JOURNAL OF CLINICAL INVESTIGATION
- Growth Inhibition of Ovarian Tumor-Initiating Cells by Niclosamide
- (2012) Y.-T. Yo et al. MOLECULAR CANCER THERAPEUTICS
- Cancer-associated lysosomal changes: friends or foes?
- (2012) T Kallunki et al. ONCOGENE
- Inhibition of Glioma Cell Lysosome Exocytosis Inhibits Glioma Invasion
- (2012) Yu Liu et al. PLoS One
- Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells
- (2012) Jing-Xuan Pan et al. Chinese Journal of Cancer
- Lysosomal Acidification Mechanisms
- (2011) Joseph A. Mindell Annual Review of Physiology
- Regulation of autophagy by lysosomal positioning
- (2011) Viktor I. Korolchuk et al. Autophagy
- Specific functions of lysosomal proteases in endocytic and autophagic pathways
- (2011) Sabrina Müller et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
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- (2008) Dong Deng et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Lysosomal Cathepsin B Participates in the Podosome-Mediated Extracellular Matrix Degradation and Invasion via Secreted Lysosomes in v-Src Fibroblasts
- (2008) C. Tu et al. CANCER RESEARCH
- The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function
- (2008) Vladimir Marshansky et al. CURRENT OPINION IN CELL BIOLOGY
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