Epilepsy, Behavioral Abnormalities, and Physiological Comorbidities in Syntaxin-Binding Protein 1 (STXBP1) Mutant Zebrafish

Loss-of-function mutations of STXBP1 in patients with epileptic encephalopathy

(2016) Toshiyuki Yamamoto et al.   BRAIN & DEVELOPMENT

The study of psychiatric disease genes and drugs in zebrafish

(2015) Martin Haesemeyer et al.   CURRENT OPINION IN NEUROBIOLOGY

Challenges in understanding psychiatric disorders and developing therapeutics: a role for zebrafish

(2015) J. M. McCammon et al.   Disease Models & Mechanisms

A second corticotropin-releasing hormone gene (CRH2) is conserved across vertebrate classes and expressed in the hindbrain of a basal Neopterygian fish, the spotted gar (Lepisosteus oculatus)

(2015) Brian P. Grone et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Sleep Differences Among Children With Autism Spectrum Disorders and Typically Developing Peers

(2015) Marilisa G. Elrod et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Divergent evolution of two corticotropin-releasing hormone (CRH) genes in teleost fishes

(2015) Brian P. Grone et al.   Frontiers in Neuroscience

Mutations in QARS, Encoding Glutaminyl-tRNA Synthetase, Cause Progressive Microcephaly, Cerebral-Cerebellar Atrophy, and Intractable Seizures

(2014) Xiaochang Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Left-Right Asymmetry Is Required for the Habenulae to Respond to Both Visual and Olfactory Stimuli

(2014) Elena Dreosti et al.   CURRENT BIOLOGY

Precise and efficient genome editing in zebrafish using the CRISPR/Cas9 system

(2014) U. Irion et al.   DEVELOPMENT

Fishing for causes and cures of motor neuron disorders

(2014) S. A. Patten et al.   Disease Models & Mechanisms

Neuropeptidergic Signaling Partitions Arousal Behaviors in Zebrafish

(2014) I. G. Woods et al.   JOURNAL OF NEUROSCIENCE

Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes

(2014) Julian Schubert et al.   NATURE GENETICS

A novel de novo STXBP1 mutation is associated with mitochondrial complex I deficiency and late-onset juvenile-onset parkinsonism

(2014) Michael J. Keogh et al.   NEUROGENETICS

GABRA1 and STXBP1: Novel genetic causes of Dravet syndrome

(2014) G. L. Carvill et al.   NEUROLOGY

CNNM2 Mutations Cause Impaired Brain Development and Seizures in Patients with Hypomagnesemia

(2014) Francisco J. Arjona et al.   PLoS Genetics

Munc18-1 haploinsufficiency results in enhanced anxiety-like behavior as determined by heart rate responses in mice

(2013) Torben Hager et al.   BEHAVIOURAL BRAIN RESEARCH

Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome

(2013) F. Mahmood et al.   Disease Models & Mechanisms

A novel mutation in STXBP1 causing epileptic encephalopathy (late onset infantile spasms) with partial respiratory chain complex IV deficiency

(2013) G. Barcia et al.   European Journal of Medical Genetics

De novo mutations in epileptic encephalopathies

(2013) et al.   NATURE

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

Folinic Acid Responsive Epilepsy in Ohtahara Syndrome Caused by STXBP1 Mutation

(2013) Winnie W.Y. Tso et al.   PEDIATRIC NEUROLOGY

Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System

(2013) Woong Y. Hwang et al.   PLoS One

Circadian clocks, rhythmic synaptic plasticity and the sleep-wake cycle in zebrafish

(2013) Idan Elbaz et al.   Frontiers in Neural Circuits

Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment

(2013) Scott C. Baraban et al.   Nature Communications

Cardiac autonomic dysfunction in West syndrome

(2012) Katrien Jansen et al.   EPILEPSY RESEARCH

A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors

(2012) Robert F. Hunt et al.   EXPERIMENTAL NEUROLOGY

Epileptic and nonepileptic features in patients with early onset epileptic encephalopathy and STXBP1 mutations

(2011) Mathieu Milh et al.   EPILEPSIA

Intellectual disability without epilepsy associated with STXBP1 disruption

(2011) Fadi F Hamdan et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genome Evolution and Meiotic Maps by Massively Parallel DNA Sequencing: Spotted Gar, an Outgroup for the Teleost Genome Duplication

(2011) Angel Amores et al.   GENETICS

Impaired neural development in a zebrafish model for Lowe syndrome

(2011) Irene Barinaga-Rementeria Ramirez et al.   HUMAN MOLECULAR GENETICS

Chemical modulation of memory formation in larval zebrafish

(2011) M. A. Wolman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac response to startle stimuli in larval zebrafish: sympathetic and parasympathetic components

(2010) Kara D. Mann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

STXBP1 mutations cause not only Ohtahara syndrome but also West syndrome-Result of Japanese cohort study

(2010) Motoko Otsuka et al.   EPILEPSIA

Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype

(2010) Y. Teng et al.   HUMAN MOLECULAR GENETICS

Optogenetic Localization and Genetic Perturbation of Saccade-Generating Neurons in Zebrafish

(2010) P. J. Schoonheim et al.   JOURNAL OF NEUROSCIENCE

Clinical spectrum of early-onset epileptic encephalopathies associated with STXBP1 mutations

(2010) L. Deprez et al.   NEUROLOGY

ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool

(2010) J. D. Sander et al.   NUCLEIC ACIDS RESEARCH

Pineal-specific agouti protein regulates teleost background adaptation

(2010) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal table of postembryonic zebrafish development: Staging by externally visible anatomy of the living fish

(2009) David M. Parichy et al.   DEVELOPMENTAL DYNAMICS

Evolution of gene function and regulatory control after whole-genome duplication: Comparative analyses in vertebrates

(2009) K. S. Kassahn et al.   GENOME RESEARCH

A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-Recessive Progressive Myoclonus Epilepsy-Ataxia Syndrome

(2008) Alexander G. Bassuk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy

(2008) Hirotomo Saitsu et al.   NATURE GENETICS