MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1

Plasma levels of mannan-binding lectin-associated serine proteases MASP-1 and MASP-2 are elevated in type 1 diabetes and correlate with glycaemic control

(2015) L. Jenny et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

MASP-1 of the complement system promotes clotting via prothrombin activation

(2015) Lorenz Jenny et al.   MOLECULAR IMMUNOLOGY

Multiple roles of complement MASP-1 at the interface of innate immune response and coagulation

(2014) József Dobó et al.   MOLECULAR IMMUNOLOGY

Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway

(2013) Márton Megyeri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The transition of prothrombin to thrombin

(2013) S. Krishnaswamy   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The control of the complement lectin pathway activation revisited: Both C1-inhibitor and antithrombin are likely physiological inhibitors, while α2-macroglobulin is not

(2013) Katalin Paréj et al.   MOLECULAR IMMUNOLOGY

Meizothrombin Is an Unexpectedly Zymogen-like Variant of Thrombin

(2012) Harlan N. Bradford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prothrombin Activation by Platelet-associated Prothrombinase Proceeds through the Prethrombin-2 Pathway via a Concerted Mechanism

(2012) Laura M. Haynes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of MASP-1 of the Complement System on Activation of Coagulation Factors and Plasma Clot Formation

(2012) Katharina Hess et al.   PLoS One

Mannose-binding lectin serine proteases and associated proteins of the lectin pathway of complement: Two genes, five proteins and many functions?

(2011) Tang Yongqing et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Mannose-Binding Lectin-Associated Serine Protease-1 Is a Significant Contributor to Coagulation in a Murine Model of Occlusive Thrombosis

(2011) L. R. La Bonte et al.   JOURNAL OF IMMUNOLOGY

Mannose-binding lectin and its associated proteases (MASPs) mediate coagulation and its deficiency is a risk factor in developing complications from infection, including disseminated intravascular coagulation

(2010) Kazue Takahashi et al.   IMMUNOBIOLOGY

Molecular Intercommunication between the Complement and Coagulation Systems

(2010) U. Amara et al.   JOURNAL OF IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

MASP-1, a Promiscuous Complement Protease: Structure of Its Catalytic Region Reveals the Basis of Its Broad Specificity

(2009) J. Dobo et al.   JOURNAL OF IMMUNOLOGY

Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions

(2009) Péter Gál et al.   MOLECULAR IMMUNOLOGY

The action of MBL-associated serine protease 1 (MASP1) on factor XIII and fibrinogen

(2008) Anders Krarup et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS