Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington’s Disease

Micro RNA-214 contributes to proteasome independent downregulation of beta catenin in Huntington's disease knock-in striatal cell model STHdhQ111/Q111

(2015) Supratim Ghatak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Corticostriatal synaptic adaptations in Huntington's disease

(2015) Joshua L Plotkin et al.   CURRENT OPINION IN NEUROBIOLOGY

A Novel Intracellular Peptide Derived from G1/S Cyclin D2 Induces Cell Death

(2014) Christiane B. de Araujo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Harnessing the Unique Structural Properties of Isolated α-Helices

(2014) Carter J. Swanson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Huntington disease: natural history, biomarkers and prospects for therapeutics

(2014) Christopher A. Ross et al.   Nature Reviews Neurology

Proteasome Inhibitors Alter Levels of Intracellular Peptides in HEK293T and SH-SY5Y Cells

(2014) Sayani Dasgupta et al.   PLoS One

Ubiquitin–proteasome system involvement in Huntington’s disease

(2014) Zaira Ortega et al.   Frontiers in Molecular Neuroscience

Molecular Architecture and Assembly of the Eukaryotic Proteasome

(2013) Robert J. Tomko et al.   Annual Review of Biochemistry

Peptide docking and structure-based characterization of peptide binding: from knowledge to know-how

(2013) Nir London et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies

(2013) Sabine Schipper-Krom et al.   FEBS LETTERS

Expanded Polyglutamine-containing N-terminal Huntingtin Fragments Are Entirely Degraded by Mammalian Proteasomes

(2013) Katrin Juenemann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Effect of Proteasome Inhibition on the Generation of the Human Leukocyte Antigen (HLA) Peptidome

(2013) Elena Milner et al.   MOLECULAR & CELLULAR PROTEOMICS

Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease

(2013) Rodrigo A Quintanilla et al.   Molecular Neurodegeneration

Alterations of the Intracellular Peptidome in Response to the Proteasome Inhibitor Bortezomib

(2013) Julia S. Gelman et al.   PLoS One

Huntington's disease: underlying molecular mechanisms and emerging concepts

(2013) John Labbadia et al.   TRENDS IN BIOCHEMICAL SCIENCES

The unique functions of tissue-specific proteasomes

(2013) Andrea Kniepert et al.   TRENDS IN BIOCHEMICAL SCIENCES

Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins

(2012) Andrew M. Pickering et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Indirect inhibition of 26S proteasome activity in a cellular model of Huntington’s disease

(2012) Mark S. Hipp et al.   JOURNAL OF CELL BIOLOGY

Peptidomic Analysis of HEK293T Cells: Effect of the Proteasome Inhibitor Epoxomicin on Intracellular Peptides

(2012) Lloyd D. Fricker et al.   JOURNAL OF PROTEOME RESEARCH

CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion

(2012) J.- M. Lee et al.   NEUROLOGY

Natural intracellular peptides can modulate the interactions of mouse brain proteins and thimet oligopeptidase with 14-3-3ε and calmodulin

(2012) Lilian C. Russo et al.   PROTEOMICS

Increasing the range of drug targets

(2012) Bernd Groner et al.   Bioengineered

Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events

(2011) S. Arastu-Kapur et al.   CLINICAL CANCER RESEARCH

Peptidomic Analysis of Human Cell Lines

(2011) Julia S. Gelman et al.   JOURNAL OF PROTEOME RESEARCH

Proteasome Activators

(2011) Beth M. Stadtmueller et al.   MOLECULAR CELL

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins

(2010) Lloyd D. Fricker   Molecular BioSystems

The Matrix Peptide Exporter HAF-1 Signals a Mitochondrial UPR by Activating the Transcription Factor ZC376.7 in C. elegans

(2010) Cole M. Haynes et al.   MOLECULAR CELL

Small Peptides Switch the Transcriptional Activity of Shavenbaby During Drosophila Embryogenesis

(2010) T. Kondo et al.   SCIENCE

Peptidic modulators of protein-protein interactions: Progress and challenges in computational design

(2009) Mor Rubinstein et al.   BIOPOLYMERS

The road less traveled: modulating signal transduction enzymes by inhibiting their protein–protein interactions

(2009) Michelle R Arkin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The 26 S Proteasome: From Basic Mechanisms to Drug Targeting

(2009) Ami Navon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

(2009) C. J. Maynard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Isotopic Labels for Quantitative Mass Spectrometry

(2008) Cain Morano et al.   ANALYTICAL CHEMISTRY

Misfolding of Proteins with a Polyglutamine Expansion Is Facilitated by Proteasomal Chaperones

(2008) Erwann Rousseau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Peptides as Natural Regulators of Cell Signaling

(2008) Fernanda M. Cunha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice

(2008) Jianjun Wang et al.   JOURNAL OF CELL BIOLOGY

Rationally designed peptide regulators of protein kinase C

(2008) Eric N. Churchill et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM