IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type Iα and IIα through Conserved Catalytic Aspartate Residues

PIP kinases define PI4,5P2 signaling specificity by association with effectors

(2015) Suyong Choi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Restoration of Na+/H+ exchanger NHE3-containing macrocomplexes ameliorates diabetes-associated fluid loss

(2015) Peijian He et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphatidylinositol 4,5-bisphosphate degradation inhibits the Na+/bicarbonate cotransporter NBCe1-B and -C variants expressed inXenopusoocytes

(2015) Ian M. Thornell et al.   JOURNAL OF PHYSIOLOGY-LONDON

IRBIT regulates CaMKIIα activity and contributes to catecholamine homeostasis through tyrosine hydroxylase phosphorylation

(2015) Katsuhiro Kawaai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Cl−as a signaling ion that potently regulates Na+/HCO3−transporters

(2015) Nikolay Shcheynikov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically Disordered Proteins and Intrinsically Disordered Protein Regions

(2014) Christopher J. Oldfield et al.   Annual Review of Biochemistry

IRBIT: A regulator of ion channels and ion transporters

(2014) Hideaki Ando et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Electrogenic Sodium Bicarbonate Cotransporter NBCe1 Is a High-Affinity Bicarbonate Carrier in Cortical Astrocytes

(2014) S. M. Theparambil et al.   JOURNAL OF NEUROSCIENCE

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

(2014) Alaji Bah et al.   NATURE

IRBIT is a novel regulator of ribonucleotide reductase in higher eukaryotes

(2014) A. Arnaoutov et al.   SCIENCE

Phosphatidylinositol 4,5-bisphosphate: Targeted production and signaling

(2013) Yue Sun et al.   BIOESSAYS

Irbit Mediates Synergy Between Ca 2+ and cAMP Signaling Pathways During Epithelial Transport in Mice

(2013) Seonghee Park et al.   GASTROENTEROLOGY

The SLC4 family of bicarbonate transporters

(2013) Michael F. Romero et al.   MOLECULAR ASPECTS OF MEDICINE

Convergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK/SPAK kinases in regulation of the Na+-HCO3- cotransporters family

(2013) J. H. Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRBIT reduces the apparent affinity for intracellular Mg2+ in inhibition of the electrogenic Na+-HCO3− cotransporter NBCe1-B

(2012) Soichiro Yamaguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The emerging role of PtdIns5P: another signalling phosphoinositide takes its place: Figure 1

(2012) Deborah L. Grainger et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins

(2012) Lukasz P Kozlowski et al.   BMC BIOINFORMATICS

Relief of autoinhibition of the electrogenic Na-HCO3 cotransporter NBCe1-B: role of IRBIT vs. amino-terminal truncation

(2011) Seong-Ki Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway

(2011) Dongki Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Preemptive Regulation of Intracellular pH in Hippocampal Neurons by a Dual Mechanism of Depolarization-Induced Alkalinization

(2011) N. Svichar et al.   JOURNAL OF NEUROSCIENCE

A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5Pand other phosphoinositides

(2010) Deborah Sarkes et al.   BIOCHEMICAL JOURNAL

PONDR-FIT: A meta-predictor of intrinsically disordered amino acids

(2010) Bin Xue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Combined Phosphoinositide and Ca2+Signals Mediating Receptor Specificity toward Neuronal Ca2+Channels

(2010) Oleg Zaika et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol-4-Phosphate 5-Kinases and Phosphatidylinositol 4,5-Bisphosphate Synthesis in the Brain

(2010) Laura A. Volpicelli-Daley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Na+/H+Exchanger NHE3 by Angiotensin II Is Mediated by Inositol 1,4,5-Triphosphate (IP3) Receptor-binding Protein Released with IP3(IRBIT) and Ca2+/Calmodulin-dependent Protein Kinase II

(2010) Peijian He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Na-coupled bicarbonate transporters of the solute carrier 4 family in the nervous system: function, localization, and relevance to neurologic function

(2010) D. Majumdar et al.   NEUROSCIENCE

Defective membrane expression of the Na+-HCO3- cotransporter NBCe1 is associated with familial migraine

(2010) M. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol 1,4,5-Triphosphate Receptor-binding Protein Released with Inositol 1,4,5-Triphosphate (IRBIT) Associates with Components of the mRNA 3′ Processing Machinery in a Phosphorylation-dependent Manner and Inhibits Polyadenylation

(2009) Hélène Kiefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis

(2009) Gregory D. Fairn et al.   JOURNAL OF CELL BIOLOGY

An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage

(2009) Hideaki Ando et al.   JOURNAL OF NEUROCHEMISTRY

Cloning, bacterial expression, and unique structure of adenosylhomocysteine hydrolase-like protein 1, or inositol 1,4,5-triphosphate receptor-binding protein from mouse kidney

(2008) Tomoharu Gomi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Prediction of disordered regions in proteins based on the meta approach

(2008) T. Ishida et al.   BIOINFORMATICS

IRBIT, Inositol 1,4,5-Triphosphate (IP3) Receptor-binding Protein Released with IP3, Binds Na+/H+Exchanger NHE3 and Activates NHE3 Activity in Response to Calcium

(2008) Peijian He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localization of electrogenic Na/bicarbonate cotransporter NBCe1 variants in rat brain

(2008) D. Majumdar et al.   NEUROSCIENCE

PtdIns5P regulation through evolution: roles in membrane trafficking?

(2008) Odile Lecompte et al.   TRENDS IN BIOCHEMICAL SCIENCES