Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells

Methyl Sulfone Manifests Anticancer Activity in a Metastatic Murine Breast Cancer Cell Line and in Human Breast Cancer Tissue - Part I: Murine 4T1 (66cl-4) Cell Line

(2017) Joan McIntyre Caron et al.   CHEMOTHERAPY

Methyl Sulfone Manifests Anticancer Activity in a Metastatic Murine Breast Cancer Cell Line and in Human Breast Cancer Tissue - Part 2: Human Breast Cancer Tissue

(2017) Joan McIntyre Caron et al.   CHEMOTHERAPY

Enhanced renoprotective effect of HIF-1α modified human adipose-derived stem cells on cisplatin-induced acute kidney injury in vivo

(2015) Wei-Wei Wang et al.   Scientific Reports

Tumors: Wounds That Do Not Heal--Redux

(2015) H. F. Dvorak   Cancer Immunology Research

The role of melanogenesis in regulation of melanoma behavior: Melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways

(2014) A. Slominski et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Fenofibrate enhances barrier function of endothelial continuum within the metastatic niche of prostate cancer cells

(2014) Katarzyna Piwowarczyk et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Multiple functions of hypoxia-regulated miR-210 in cancer

(2014) Qin Qin et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies

(2014) Y Aye et al.   ONCOGENE

Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis

(2014) K. W. Sinkevicius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-regulated microRNAs in human cancer

(2013) Guomin Shen et al.   ACTA PHARMACOLOGICA SINICA

PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells

(2013) William J. Israelsen et al.   CELL

The essential nature of iron usage and regulation

(2013) Jerry Kaplan et al.   CURRENT BIOLOGY

Roles of the hepcidin–ferroportin axis and iron in cancer

(2013) Xian-Ning Wu et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis

(2013) Pallavi Chaturvedi et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia Contributes to Melanoma Heterogeneity by Triggering HIF1α-Dependent Phenotype Switching

(2013) Daniel S. Widmer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The VEGF Pathway in Cancer and Disease: Responses, Resistance, and the Path Forward

(2013) M. W. Kieran et al.   Cold Spring Harbor Perspectives in Medicine

Tumour Hypoxia Affects the Responsiveness of Cancer Cells to Chemotherapy and Promotes Cancer Progression

(2012) Jean-Philippe Cosse et al.   Anti-Cancer Agents in Medicinal Chemistry

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

The prognostic value of vascular endothelial growth factor in ovarian cancer: A systematic review and meta-analysis

(2012) Lei Yu et al.   GYNECOLOGIC ONCOLOGY

Cysteine 70 of Ankyrin-G IsS-Palmitoylated and Is Required for Function of Ankyrin-G in Membrane Domain Assembly

(2012) Meng He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Micromanaging Iron Homeostasis

(2012) Yusuke Yoshioka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The molecular basis of iron overload disorders and iron-linked anemias

(2011) Jerry Kaplan et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Microtubule disruption targets HIF-1α mRNA to cytoplasmic P-bodies for translational repression

(2011) Marisa Carbonaro et al.   JOURNAL OF CELL BIOLOGY

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

(2011) Aude Carreau et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease

(2010) Hong Ye et al.   BIOCHEMISTRY

Effects of iron deficiency and iron overload on angiogenesis and oxidative stress—a potential dual role for iron in breast cancer

(2010) Jinlong Jian et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU

(2010) Elena Favaro et al.   PLoS One

Methyl Sulfone Induces Loss of Metastatic Properties and Reemergence of Normal Phenotypes in a Metastatic Cloudman S-91 (M3) Murine Melanoma Cell Line

(2010) Joan McIntyre Caron et al.   PLoS One

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Mitochondrial Dysfunction Leads to Nuclear Genome Instability via an Iron-Sulfur Cluster Defect

(2009) Joshua R. Veatch et al.   CELL

MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2

(2009) Stephen Y. Chan et al.   Cell Metabolism

Hypoxia and Radiation Therapy: Past History, Ongoing Research, and Future Promise

(2009) Sara Rockwell et al.   CURRENT MOLECULAR MEDICINE

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

(2009) Xin Huang et al.   MOLECULAR CELL

The Pervasive Presence of Fluctuating Oxygenation in Tumors

(2008) L. I. Cardenas-Navia et al.   CANCER RESEARCH

Role of hypoxia-inducible factor in cell survival during myocardial ischemia–reperfusion

(2008) G Loor et al.   CELL DEATH AND DIFFERENTIATION