Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions

Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria

(2015) Michelle J. Boyle et al.   IMMUNITY

Alternative splicing modulates Kv channel clustering through a molecular ball and chain mechanism

(2015) Nitzan Zandany et al.   Nature Communications

Conformational Dynamics and Antigenicity in the Disordered Malaria Antigen Merozoite Surface Protein 2

(2015) Christopher A. MacRaild et al.   PLoS One

Direct interaction between EFL1 and SBDS is mediated by an intrinsically disordered insertion domain

(2014) Nozomi Asano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DISOPRED3: precise disordered region predictions with annotated protein-binding activity

(2014) David T. Jones et al.   BIOINFORMATICS

A comprehensive evaluation of rodent malaria parasite genomes and gene expression

(2014) Thomas D Otto et al.   BMC BIOLOGY

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Epitope distribution in ordered and disordered protein regions — Part A. T-cell epitope frequency, affinity and hydropathy

(2014) Nenad S. Mitić et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Genome-Wide Analysis of Selection on the Malaria Parasite Plasmodium falciparum in West African Populations of Differing Infection Endemicity

(2014) Victor A. Mobegi et al.   MOLECULAR BIOLOGY AND EVOLUTION

Protective Epitopes of the Plasmodium falciparum SERA5 Malaria Vaccine Reside in Intrinsically Unstructured N-Terminal Repetitive Sequences

(2014) Masanori Yagi et al.   PLoS One

Minute Time Scale Prolyl Isomerization Governs Antibody Recognition of an Intrinsically Disordered Immunodominant Epitope

(2013) Marisol Fassolari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection

(2013) Lander Foquet et al.   JOURNAL OF CLINICAL INVESTIGATION

The intrinsically disordered distal face of nucleoplasmin recognizes distinct oligomerization states of histones

(2013) I. Ramos et al.   NUCLEIC ACIDS RESEARCH

Intrinsically disordered regions of nucleophosmin/B23 regulate its RNA binding activity through their inter- and intra-molecular association

(2013) M. Hisaoka et al.   NUCLEIC ACIDS RESEARCH

Vaccination with Conserved Regions of Erythrocyte-Binding Antigens Induces Neutralizing Antibodies against Multiple Strains of Plasmodium falciparum

(2013) Julie Healer et al.   PLoS One

Antigenic Characterization of an Intrinsically Unstructured Protein, Plasmodium falciparum Merozoite Surface Protein 2

(2012) Christopher G. Adda et al.   INFECTION AND IMMUNITY

Orderly order in protein intrinsic disorder distribution: disorder in 3500 proteomes from viruses and the three domains of life

(2012) Bin Xue et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Cell Biological Characterization of the Malaria Vaccine Candidate Trophozoite Exported Protein 1

(2012) Caroline Kulangara et al.   PLoS One

Reliable B Cell Epitope Predictions: Impacts of Method Development and Improved Benchmarking

(2012) Jens Vindahl Kringelum et al.   PLoS Computational Biology

Increased Polymorphism Near Low-Complexity Sequences across the Genomes of Plasmodium falciparum Isolates

(2011) Wilfried Haerty et al.   Genome Biology and Evolution

A Phase 1 Trial of MSP2-C1, a Blood-Stage Malaria Vaccine Containing 2 Isoforms of MSP2 Formulated with Montanide® ISA 720

(2011) James S. McCarthy et al.   PLoS One

Proteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions in proteins

(2011) Johan Nilsson et al.   GENOME BIOLOGY

Protein tandem repeats - the more perfect, the less structured

(2010) Julien Jorda et al.   FEBS Journal

Upregulated Expression of B-Cell Antigen Family Tandem Repeat Proteins by Leishmania Amastigotes

(2010) Y. Goto et al.   INFECTION AND IMMUNITY

Reticulocyte and Erythrocyte Binding-Like Proteins Function Cooperatively in Invasion of Human Erythrocytes by Malaria Parasites

(2010) Sash Lopaticki et al.   INFECTION AND IMMUNITY

Structure and Properties of a Complex of α-Synuclein and a Single-Domain Camelid Antibody

(2010) Erwin J. De Genst et al.   JOURNAL OF MOLECULAR BIOLOGY

Fab′-Induced Folding of Antigenic N-Terminal Peptides from Intrinsically Disordered HIV-1 Tat Revealed by X-ray Crystallography

(2010) Jennifer Serrière et al.   JOURNAL OF MOLECULAR BIOLOGY

Allele Frequency-Based and Polymorphism-Versus-Divergence Indices of Balancing Selection in a New Filtered Set of Polymorphic Genes in Plasmodium falciparum

(2010) L. I. Ochola et al.   MOLECULAR BIOLOGY AND EVOLUTION

T-REKS: identification of Tandem REpeats in sequences with a K-meanS based algorithm

(2009) Julien Jorda et al.   BIOINFORMATICS

NN-align. An artificial neural network-based alignment algorithm for MHC class II peptide binding prediction

(2009) Morten Nielsen et al.   BMC BIOINFORMATICS

Major Species-Specific Antibody Epitopes of the Ehrlichia chaffeensis p120 and E. canis p140 Orthologs in Surface-Exposed Tandem Repeat Regions

(2009) T. Luo et al.   Clinical and Vaccine Immunology

Polymorphisms in Erythrocyte Binding Antigens 140 and 181 Affect Function and Binding but Not Receptor Specificity in Plasmodium falciparum

(2009) A. G. Maier et al.   INFECTION AND IMMUNITY

Antibodies to Reticulocyte Binding Protein-Like Homologue 4 Inhibit Invasion of Plasmodium falciparum into Human Erythrocytes

(2009) W.-H. Tham et al.   INFECTION AND IMMUNITY

Vaccine Potentials of an Intrinsically Unstructured Fragment Derived from the Blood Stage-Associated Plasmodium falciparum Protein PFF0165c

(2009) S. Olugbile et al.   INFECTION AND IMMUNITY

Structure of thePlasmodium falciparumCircumsporozoite Protein, a Leading Malaria Vaccine Candidate

(2009) Matthew L. Plassmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils

(2009) Christopher G. Adda et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Immunological Dominance of Trypanosoma cruzi Tandem Repeat Proteins

(2008) Y. Goto et al.   INFECTION AND IMMUNITY

Solution Conformation, Backbone Dynamics and Lipid Interactions of the Intrinsically Unstructured Malaria Surface Protein MSP2

(2008) Xuecheng Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure

(2008) Chiawei W. Tsai et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The genome of the simian and human malaria parasite Plasmodium knowlesi

(2008) A. Pain et al.   NATURE

Comparative genomics of the neglected human malaria parasite Plasmodium vivax

(2008) Jane M. Carlton et al.   NATURE

PlasmoDB: a functional genomic database for malaria parasites

(2008) C. Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH