Acinetobacter baumannii Repeatedly Evolves a Hypermutator Phenotype in Response to Tigecycline That Effectively Surveys Evolutionary Trajectories to Resistance

The Ribosomal S10 Protein Is a General Target for Decreased Tigecycline Susceptibility

(2015) Kathryn Beabout et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiotic Modulation of Capsular Exopolysaccharide and Virulence in Acinetobacter baumannii

(2015) Edward Geisinger et al.   PLoS Pathogens

Genomic Analysis of Reduced Susceptibility to Tigecycline in Enterococcus faecium

(2014) Vincent Cattoir et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The spectrum of adaptive mutations in experimental evolution

(2014) Gregory I. Lang et al.   GENOMICS

Mutations in Global Regulators Lead to Metabolic Selection during Adaptation to Complex Environments

(2014) Gerda Saxer et al.   PLoS Genetics

RND-Type Efflux Pumps in Multidrug-Resistant Clinical Isolates of Acinetobacter baumannii: Major Role for AdeABC Overexpression and AdeRS Mutations

(2013) Eun-Jeong Yoon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genomics of KPC-Producing Klebsiella pneumoniae Sequence Type 512 Clone Highlights the Role of RamR and Ribosomal S10 Protein Mutations in Conferring Tigecycline Resistance

(2013) Laura Villa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Adaptation of Enterococcus faecalis to Daptomycin Reveals an Ordered Progression to Resistance

(2013) Corwin Miller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Method for generating marker-less gene deletions in multidrug-resistant Acinetobacter baumannii

(2013) Ismawati Amin et al.   BMC MICROBIOLOGY

Decreased susceptibility to tigecycline in Acinetobacter baumannii mediated by a mutation in trm encoding SAM-dependent methyltransferase

(2013) Q. Chen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Variation in the Complex Carbohydrate Biosynthesis Loci of Acinetobacter baumannii Genomes

(2013) Johanna J. Kenyon et al.   PLoS One

Genome Analysis of a Transmissible Lineage of Pseudomonas aeruginosa Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators

(2013) Rasmus Lykke Marvig et al.   PLoS Genetics

Expression of the Resistance-Nodulation-Cell Division Pump AdeIJK in Acinetobacter baumannii Is Regulated by AdeN, a TetR-Type Regulator

(2012) Nicolas Rosenfeld et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Protein Synthesis Factors (RF1, RF2, RF3, RRF, and tmRNA) and Peptidyl-tRNA Hydrolase Rescue Stalled Ribosomes at Sense Codons

(2012) Serafín Vivanco-Domínguez et al.   JOURNAL OF MOLECULAR BIOLOGY

A Truncated AdeS Kinase Protein Generated by ISAba1 Insertion Correlates with Tigecycline Resistance in Acinetobacter baumannii

(2012) Jun-Ren Sun et al.   PLoS One

General and inducible hypermutation facilitate parallel adaptation in Pseudomonas aeruginosa despite divergent mutation spectra

(2012) M. R. Weigand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small changes in enzyme function can lead to surprisingly large fitness effects during adaptive evolution of antibiotic resistance

(2012) K. Walkiewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing

(2012) H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteins that bind and move lipids: MsbA and NPC1

(2011) Gavin King et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Whole-genome comparison of two Acinetobacter baumannii isolates from a single patient, where resistance developed during tigecycline therapy

(2011) Michael Hornsey et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Genome Sequence of a Dominant, Multidrug-Resistant Acinetobacter baumannii Strain, TCDC-AB0715

(2011) C.-C. Chen et al.   JOURNAL OF BACTERIOLOGY

Overexpression of the adeB Gene in Clinical Isolates of Tigecycline-Nonsusceptible Acinetobacter baumannii without Insertion Mutations in adeRS

(2010) J.-R. Sun et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Overexpression of Resistance-Nodulation-Cell Division Pump AdeFGH Confers Multidrug Resistance in Acinetobacter baumannii

(2010) S. Coyne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efflux-Mediated Antibiotic Resistance inAcinetobacterspp.

(2010) Sébastien Coyne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A rapid and simple method for constructing stable mutants of Acinetobacter baumannii

(2010) Jesús Aranda et al.   BMC MICROBIOLOGY

Multidrug-resistant Acinetobacter baumannii: mechanisms of virulence and resistance

(2010) Nicola C. Gordon et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

AdeABC-mediated efflux and tigecycline MICs for epidemic clones of Acinetobacter baumannii

(2010) M. Hornsey et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Repeatability of Adaptive Radiation During Long-Term Experimental Evolution of Escherichia coli in a Multiple Nutrient Environment

(2010) Gerda Saxer et al.   PLoS One

The A–Z of bacterial translation inhibitors

(2009) Daniel N. Wilson   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Genome evolution and adaptation in a long-term experiment with Escherichia coli

(2009) Jeffrey E. Barrick et al.   NATURE

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols