Altered FGF Signaling Pathways Impair Cell Proliferation and Elevation of Palate Shelves

Neural crest-specific deletion of Ldb1 leads to cleft secondary palate with impaired palatal shelf elevation

(2014) Asma Almaidhan et al.   BMC DEVELOPMENTAL BIOLOGY

Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis

(2013) J. Zhou et al.   DEVELOPMENT

Type 1 Fibroblast Growth Factor Receptor in Cranial Neural Crest Cell-derived Mesenchyme Is Required for Palatogenesis

(2013) Cong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular targets on the horizon for kidney and urothelial cancer

(2013) Joaquim Bellmunt et al.   Nature Reviews Clinical Oncology

Exploring mechanisms of FGF signalling through the lens of structural biology

(2013) Regina Goetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Delineating a Conserved Genetic Cassette Promoting Outgrowth of Body Appendages

(2013) Congxing Lin et al.   PLoS Genetics

Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate

(2012) Andrew D Economou et al.   NATURE GENETICS

SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis

(2011) J. Li et al.   DEVELOPMENT

Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development

(2011) J. O. Bush et al.   DEVELOPMENT

Sprouty2 controls proliferation of palate mesenchymal cells via fibroblast growth factor signaling

(2010) Kaori Matsumura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

(2010) Y. Ahn et al.   DEVELOPMENT

Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation

(2010) H. Enomoto et al.   DEVELOPMENT

The role of FGF/Erk signaling in pluripotent cells

(2010) F. Lanner et al.   DEVELOPMENT

Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression

(2010) Fenglei He et al.   DEVELOPMENTAL BIOLOGY

Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate

(2010) A. K. Snyder-Warwick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice

(2009) J. Han et al.   DEVELOPMENT

Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth

(2009) Y. Lan et al.   DEVELOPMENT

Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development

(2009) Yang Gao et al.   DEVELOPMENTAL BIOLOGY

Signaling integration in the rugae growth zone directs sequential SHH signaling center formation during the rostral outgrowth of the palate

(2009) Ian C. Welsh et al.   DEVELOPMENTAL BIOLOGY

Hand2 is required in the epithelium for palatogenesis in mice

(2009) Wei Xiong et al.   DEVELOPMENTAL BIOLOGY

Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development

(2009) Jianquan Chen et al.   DEVELOPMENTAL BIOLOGY

Epithelial-specific requirement of FGFR2 signaling during tooth and palate development

(2009) Ryoichi Hosokawa et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development

(2008) Sophie Pantalacci et al.   BMC DEVELOPMENTAL BIOLOGY

The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice

(2008) W. Liu et al.   DEVELOPMENT

Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development

(2008) F. He et al.   DEVELOPMENT

Mice with an anterior cleft of the palate survive neonatal lethality

(2008) Shuping Gu et al.   DEVELOPMENTAL DYNAMICS

Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice

(2008) Shuping Gu et al.   MECHANISMS OF DEVELOPMENT