The Viral Mimetic Polyinosinic:Polycytidylic Acid Alters the Growth Characteristics of Small Intestinal and Colonic Crypt Cultures

An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium

(2015) Carmen Pin et al.   Integrative Biology

Distinct Human Stem Cell Populations in Small and Large Intestine

(2015) Julie M. Cramer et al.   PLoS One

Toll-like receptor expression in crypt epithelial cells, putative stem cells and intestinal myofibroblasts isolated from controls and patients with inflammatory bowel disease

(2014) M. Brown et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract

(2014) Jennifer Foulke-Abel et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ

(2014) Henner F. Farin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium

(2014) F Sommer et al.   Mucosal Immunology

Intraluminal Administration of Poly I:C Causes an Enteropathy That Is Exacerbated by Administration of Oral Dietary Antigen

(2014) Romina E. Araya et al.   PLoS One

Adult Stem Cells in the Small Intestine Are Intrinsically Programmed with Their Location-Specific Function

(2014) Sabine Middendorp et al.   STEM CELLS

Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome

(2014) Naoki Takemura et al.   Nature Communications

Intestinal stem cells remain viable after prolonged tissue storage

(2013) Megan K. Fuller et al.   CELL AND TISSUE RESEARCH

Double-Stranded RNA of Intestinal Commensal but Not Pathogenic Bacteria Triggers Production of Protective Interferon-β

(2013) Tadaomi Kawashima et al.   IMMUNITY

A functional CFTR assay using primary cystic fibrosis intestinal organoids

(2013) Johanna F Dekkers et al.   NATURE MEDICINE

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

A nomenclature for intestinal in vitro cultures

(2012) Matthias Stelzner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Activation of Innate Immunity Is Required for Efficient Nuclear Reprogramming

(2012) Jieun Lee et al.   CELL

On the biomechanics of stem cell niche formation in the gut - modelling growing organoids

(2012) Peter Buske et al.   FEBS Journal

Identification of a cKit+ Colonic Crypt Base Secretory Cell That Supports Lgr5+ Stem Cells in Mice

(2012) Michael E. Rothenberg et al.   GASTROENTEROLOGY

TLR3 activation efficiency by high or low molecular mass poly I:C

(2012) Yu Zhou et al.   Innate Immunity

TLR3, TRIF, and Caspase 8 Determine Double-Stranded RNA-Induced Epithelial Cell Death and Survival In Vivo

(2012) C. S. McAllister et al.   JOURNAL OF IMMUNOLOGY

Intestinal crypts reproducibly expand in culture

(2012) Megan K. Fuller et al.   JOURNAL OF SURGICAL RESEARCH

Mouse Background Strain Profoundly Influences Paneth Cell Function and Intestinal Microbial Composition

(2012) Ajay S. Gulati et al.   PLoS One

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)

(2012) A. Durand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Dependent TLR3 Expression of the Intestinal Epithelium Contributes to Rotavirus Susceptibility

(2012) Johanna Pott et al.   PLoS Pathogens

TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis

(2012) Tsukasa Seya et al.   OncoImmunology

2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis

(2011) Jacqueline E Tate et al.   LANCET INFECTIOUS DISEASES

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

(2011) S. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Rotavirus and coxsackievirus infection activated different profiles of toll-like receptors and chemokines in intestinal epithelial cells

(2009) Jin Xu et al.   INFLAMMATION RESEARCH

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE