Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA
Authors
Keywords
NMR spectroscopy, Crystal structure, Enzyme assays, Antimicrobial resistance, Disulfide bonds, Cysteine, Enzyme inhibitors, Library screening
Journal
PLoS One
Volume 10, Issue 7, Pages e0133805
Publisher
Public Library of Science (PLoS)
Online
2015-07-31
DOI
10.1371/journal.pone.0133805
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Peptide Inhibitors of the Escherichia coli DsbA Oxidative Machinery Essential for Bacterial Virulence
- (2014) Wilko Duprez et al. JOURNAL OF MEDICINAL CHEMISTRY
- Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo
- (2013) Philip M. Ireland et al. ANTIOXIDANTS & REDOX SIGNALING
- TMC207 becomes bedaquiline, a new anti-TB drug
- (2013) Juan Carlos Palomino et al. Future Microbiology
- Antibiotics in the clinical pipeline in 2013
- (2013) Mark S Butler et al. JOURNAL OF ANTIBIOTICS
- Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes
- (2013) Fabian Kurth et al. PLoS One
- Screening Strategies to Identify New Antibiotics
- (2012) Mark S. Butler et al. CURRENT DRUG TARGETS
- Conformer Generation with OMEGA: Learning from the Data Set and the Analysis of Failures
- (2012) Paul C. D. Hawkins et al. Journal of Chemical Information and Modeling
- Lipo-γ-AApeptides as a New Class of Potent and Broad-Spectrum Antimicrobial Agents
- (2012) Youhong Niu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure and Function of DsbA, a Key Bacterial Oxidative Folding Catalyst
- (2011) Stephen R. Shouldice et al. ANTIOXIDANTS & REDOX SIGNALING
- Beyond natural antimicrobial peptides: multimeric peptides and other peptidomimetic approaches
- (2011) Andrea Giuliani et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Peptides and Proteins as a Continuing Exciting Source of Inspiration for Peptidomimetics
- (2011) Rob M. J. Liskamp et al. CHEMBIOCHEM
- Fidaxomicin: A Novel Macrocyclic Antibiotic Approved for Treatment of Clostridium difficile Infection
- (2011) A. A. Venugopal et al. CLINICAL INFECTIOUS DISEASES
- Antibiotics in the clinical pipeline in 2011
- (2011) Mark S Butler et al. JOURNAL OF ANTIBIOTICS
- Tripeptide Motifs in Biology: Targets for Peptidomimetic Design
- (2011) Phuc Ung et al. JOURNAL OF MEDICINAL CHEMISTRY
- A guiding hand for antibiotics
- (2011) Dan Jones NATURE REVIEWS DRUG DISCOVERY
- The expanding scope of antimicrobial peptide structures and their modes of action
- (2011) Leonard T. Nguyen et al. TRENDS IN BIOTECHNOLOGY
- Discovering new antimicrobial agents
- (2010) Robert C. Moellering INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database
- (2010) Paul C. D. Hawkins et al. Journal of Chemical Information and Modeling
- The antibacterial lead discovery challenge
- (2010) NATURE REVIEWS DRUG DISCOVERY
- Anti-virulence strategies to combat bacteria-mediated disease
- (2010) David A. Rasko et al. NATURE REVIEWS DRUG DISCOVERY
- Strategies to prolong the plasma residence time of peptide drugs
- (2010) Lisa Pollaro et al. MedChemComm
- Detecting Folding Intermediates of a Protein as It Passes through the Bacterial Translocation Channel
- (2009) Hiroshi Kadokura et al. CELL
- New approaches in peptide antibiotics
- (2009) Martti Vaara CURRENT OPINION IN PHARMACOLOGY
- Dynamic nature of disulphide bond formation catalysts revealed by crystal structures of DsbB
- (2009) Kenji Inaba et al. EMBO JOURNAL
- Has the era of untreatable infections arrived?
- (2009) D. M. Livermore JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Characterization of Two Homologous Disulfide Bond Systems Involved in Virulence Factor Biogenesis in Uropathogenic Escherichia coli CFT073
- (2009) M. Totsika et al. JOURNAL OF BACTERIOLOGY
- Disulfide Bond Formation System in Escherichia coli
- (2009) K. Inaba JOURNAL OF BIOCHEMISTRY
- Structure and Function of the Oxidoreductase DsbA1 from Neisseria meningitidis
- (2009) Julian P. Vivian et al. JOURNAL OF MOLECULAR BIOLOGY
- DSB proteins and bacterial pathogenicity
- (2009) Begoña Heras et al. NATURE REVIEWS MICROBIOLOGY
- Antimicrobial peptide mimics for improved therapeutic properties
- (2008) Shahar Rotem et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
- (2008) Helen W. Boucher et al. CLINICAL INFECTIOUS DISEASES
- The disulfide bond formation (Dsb) system
- (2008) K ITO et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Whither antibacterial drug discovery?
- (2008) Steven J. Projan DRUG DISCOVERY TODAY
- Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB
- (2008) Goran Malojčić et al. FEBS LETTERS
- Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides
- (2008) N. P. Chongsiriwatana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bacterial species exhibit diversity in their mechanisms and capacity for protein disulfide bond formation
- (2008) R. J. Dutton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and mechanisms of the DsbB–DsbA disulfide bond generation machine
- (2007) Kenji Inaba et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now