Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection

Suppression of NLRX1 in chronic obstructive pulmonary disease

(2015) Min-Jong Kang et al.   JOURNAL OF CLINICAL INVESTIGATION

A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity

(2015) Shuxi Qiao et al.   Nature Communications

Review article: associations betweenHelicobacter pyloriand obesity - an ecological study

(2014) N. Lender et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

WildCARDs: Inflammatory caspases directly detect LPS

(2014) Jon Alan Hagar et al.   CELL RESEARCH

Chemokines and Antimicrobial Peptides Have acag-Dependent Early Response to Helicobacter pylori Infection in Primary Human Gastric Epithelial Cells

(2014) Pascale Mustapha et al.   INFECTION AND IMMUNITY

Emerging Significance of NLRs in Inflammatory Bowel Disease

(2014) Beckley K. Davis et al.   INFLAMMATORY BOWEL DISEASES

Regulated in Development and DNA Damage 1 Is Necessary for Hyperglycemia-induced Vascular Endothelial Growth Factor Expression in the Retina of Diabetic Rodents

(2014) Michael D. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Helicobacter pyloriInfection Activates Src Homology-2 Domain–Containing Phosphatase 2 To Suppress IFN-γ Signaling

(2014) Yu-Chih Wang et al.   JOURNAL OF IMMUNOLOGY

Heme Oxygenase-1 Dysregulates Macrophage Polarization and the Immune Response toHelicobacter pylori

(2014) Alain P. Gobert et al.   JOURNAL OF IMMUNOLOGY

Protease-activated receptor 1 suppresses Helicobacter pylori gastritis via the inhibition of macrophage cytokine secretion and interferon regulatory factor 5

(2014) Y-T Chionh et al.   Mucosal Immunology

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

The NOD-Like Receptor Signalling Pathway in Helicobacter pylori Infection and Related Gastric Cancer: A Case-Control Study and Gene Expression Analyses

(2014) Natalia Castaño-Rodríguez et al.   PLoS One

Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10

(2014) D. B. Engler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein

(2014) J. Jaworska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling

(2014) M. D. Dennis et al.   Science Signaling

Systems Modeling of the Role of Interleukin-21 in the Maintenance of Effector CD4+ T Cell Responses during Chronic Helicobacter pylori Infection

(2014) A. Carbo et al.   mBio

Non-Inflammasome Forming NLRs in Inflammation and Tumorigenesis

(2014) Irving Coy Allen   Frontiers in Immunology

Helicobacter pylori Infection in a Pig Model Is Dominated by Th1 and Cytotoxic CD8+T Cell Responses

(2013) Barbara Kronsteiner et al.   INFECTION AND IMMUNITY

Identification of Genetic Loci Associated With Helicobacter pylori Serologic Status

(2013) Julia Mayerle et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

(2013) Nina R. Salama et al.   NATURE REVIEWS MICROBIOLOGY

Predictive Computational Modeling of the Mucosal Immune Responses during Helicobacter pylori Infection

(2013) Adria Carbo et al.   PLoS One

TLR2 Mediates Helicobacter pylori–Induced Tolerogenic Immune Response in Mice

(2013) Xia Sun et al.   PLoS One

Systems Modeling of Molecular Mechanisms Controlling Cytokine-driven CD4+ T Cell Differentiation and Phenotype Plasticity

(2013) Adria Carbo et al.   PLoS Computational Biology

Interleukin-8 is the single most up-regulated gene in whole genome profiling of H. pylori exposed gastric epithelial cells

(2012) Lars L Eftang et al.   BMC MICROBIOLOGY

Differential Interleukin-10 (IL-10) and IL-23 Production by Human Blood Monocytes and Dendritic Cells in Response to Commensal Enteric Bacteria

(2012) Jennifer Manuzak et al.   Clinical and Vaccine Immunology

ENteric Immunity SImulator: A Tool for In Silico Study of Gastroenteric Infections

(2012) K. V. Wendelsdorf et al.   IEEE TRANSACTIONS ON NANOBIOSCIENCE

The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

(2012) Yu Lei et al.   IMMUNITY

Inflammatory Monocyte Recruitment Is Regulated by Interleukin-23 during Systemic Bacterial Infection

(2012) Mohanalaxmi Indramohan et al.   INFECTION AND IMMUNITY

NLRX1 does not inhibit MAVS-dependent antiviral signalling

(2012) Fraser Soares et al.   Innate Immunity

Novel Bacterial Lipoprotein Structures Conserved in Low-GC Content Gram-positive Bacteria Are Recognized by Toll-like Receptor 2

(2012) Kenji Kurokawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

(2012) Monika Schneider et al.   NATURE IMMUNOLOGY

Helicobacter pylori Colonization Ameliorates Glucose Homeostasis in Mice through a PPAR γ-Dependent Mechanism

(2012) Josep Bassaganya-Riera et al.   PLoS One

Disease Tolerance as a Defense Strategy

(2012) R. Medzhitov et al.   SCIENCE

Transcriptome Complexity and Riboregulation in the Human Pathogen Helicobacter pylori

(2012) Sandy R. Pernitzsch et al.   Frontiers in Cellular and Infection Microbiology

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

H. pylori exploits and manipulates innate and adaptive immune cell signaling pathways to establish persistent infection

(2011) Anne Müller et al.   Cell Communication and Signaling

NLRX1/NOD5 deficiency does not affect MAVS signalling

(2011) M Rebsamen et al.   CELL DEATH AND DIFFERENTIATION

Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease

(2011) Clara Abraham et al.   GASTROENTEROLOGY

NLRX1 Negatively Regulates TLR-Induced NF-κB Signaling by Targeting TRAF6 and IKK

(2011) Xiaojun Xia et al.   IMMUNITY

NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

(2011) Irving C. Allen et al.   IMMUNITY

Return to homeostasis: downregulation of NF-κB responses

(2011) Jürgen Ruland   NATURE IMMUNOLOGY

Helicobacter pylori may protect against IBD—a mechanistic insight

(2011) Shreeya Nanda   Nature Reviews Gastroenterology & Hepatology

Induction of TLR-2 and TLR-5 Expression by Helicobacter pylori Switches cagPAI-Dependent Signalling Leading to the Secretion of IL-8 and TNF-α

(2011) Suneesh Kumar Pachathundikandi et al.   PLoS One

Helicobacter pylori versus the Host: Remodeling of the Bacterial Outer Membrane Is Required for Survival in the Gastric Mucosa

(2011) Thomas W. Cullen et al.   PLoS Pathogens

A National Study of Helicobactor pylori Infection in Gastric Biopsy Specimens

(2010) Amnon Sonnenberg et al.   GASTROENTEROLOGY

Invasion and Multiplication of Helicobacter pylori in Gastric Epithelial Cells and Implications for Antibiotic Resistance

(2010) Y.-T. Chu et al.   INFECTION AND IMMUNITY

Host-Interactive Genes in Amerindian Helicobacter pylori Diverge from Their Old World Homologs and Mediate Inflammatory Responses

(2010) S. P. Mane et al.   JOURNAL OF BACTERIOLOGY

Enhancement of Reactive Oxygen Species Production and Chlamydial Infection by the Mitochondrial Nod-like Family Member NLRX1

(2010) Ali A. Abdul-Sater et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway

(2010) Tomohiro Watanabe et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR-2-Activated B Cells Suppress Helicobacter-Induced Preneoplastic Gastric Immunopathology by Inducing T Regulatory-1 Cells

(2010) A. Sayi et al.   JOURNAL OF IMMUNOLOGY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Extracellular and Intracellular Pattern Recognition Receptors Cooperate in the Recognition of Helicobacter pylori

(2009) Roland Rad et al.   GASTROENTEROLOGY

Blimp-1/PRDM1 Mediates Transcriptional Suppression of the NLR Gene NLRP12/Monarch-1

(2009) C. A. Lord et al.   JOURNAL OF IMMUNOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Disappearing Microbiota: Helicobacter pylori Protection against Esophageal Adenocarcinoma

(2008) M. J. Blaser   Cancer Prevention Research

NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production

(2008) Ivan Tattoli et al.   EMBO REPORTS

The Autophagic Induction in Helicobacter pylori-Infected Macrophage

(2008) Ya-Hui Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Host-Bacterial Interactions in Helicobacter pylori Infection

(2008) Manuel R. Amieva et al.   GASTROENTEROLOGY

NLRX1 is a regulator of mitochondrial antiviral immunity

(2008) Chris B. Moore et al.   NATURE