Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat

Prospects for Lentiviral Vector Mediated Prostaglandin F Synthase Gene Delivery in Monkey EyesIn vivo

(2014) Eun Suk Lee et al.   CURRENT EYE RESEARCH

Retinal transduction profiles by high-capacity viral vectors

(2014) A Puppo et al.   GENE THERAPY

The Dysfunction of the Trabecular Meshwork During Glaucoma Course

(2014) Sergio Claudio Saccà et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Trabecular Meshwork in Normal Eyes and in Exfoliation Glaucoma

(2014) Carol A. Rasmussen et al.   JOURNAL OF GLAUCOMA

The role of transforming growth factor β in glaucoma and the therapeutic implications

(2013) Mark A Prendes et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Optimizing gene transfer to conventional outflow cells in living mouse eyes

(2013) G. Li et al.   EXPERIMENTAL EYE RESEARCH

Vesicular Stomatitis Virus Glycoprotein– and Venezuelan Equine Encephalitis Virus-Derived Glycoprotein–Pseudotyped Lentivirus Vectors Differentially Transduce Corneal Endothelium, Trabecular Meshwork, and Human Photoreceptors

(2013) Daniel M. Lipinski et al.   HUMAN GENE THERAPY

Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators

(2013) Andrew C. Weitz et al.   JOURNAL OF NEUROPHYSIOLOGY

Corneal Gene Therapy: Basic Science and Translational Perspective

(2013) Rajiv R. Mohan et al.   Ocular Surface

Optimization of the Capsid of Recombinant Adeno-Associated Virus 2 (AAV2) Vectors: The Final Threshold?

(2013) George V. Aslanidi et al.   PLoS One

Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors

(2013) Christine N. Kay et al.   PLoS One

Tissue Plasminogen Activator in Trabecular Meshwork Attenuates Steroid Induced Outflow Resistance in Mice

(2013) Sandeep Kumar et al.   PLoS One

Bioengineering of AAV2 Capsid at Specific Serine, Threonine, or Lysine Residues Improves Its Transduction Efficiency in Vitro and in Vivo

(2013) Nishanth Gabriel et al.   Human Gene Therapy Methods

Connective Tissue Growth Factor Causes Glaucoma by Modifying the Actin Cytoskeleton of the Trabecular Meshwork

(2012) Benjamin Junglas et al.   AMERICAN JOURNAL OF PATHOLOGY

Gene therapy for corneal dystrophies and disease, where are we?

(2012) Keryn A. Williams et al.   CURRENT OPINION IN OPHTHALMOLOGY

Pathological consequences of long-term mitochondrial oxidative stress in the mouse retinal pigment epithelium

(2012) Soo-jung Seo et al.   EXPERIMENTAL EYE RESEARCH

Structural Insight into the Unique Properties of Adeno-Associated Virus Serotype 9

(2012) M. A. DiMattia et al.   JOURNAL OF VIROLOGY

The AAV Vector Toolkit: Poised at the Clinical Crossroads

(2012) Aravind Asokan et al.   MOLECULAR THERAPY

Corneal Transduction by Intra-Stromal Injection of AAV Vectors In Vivo in the Mouse and Ex Vivo in Human Explants

(2012) Claire Hippert et al.   PLoS One

High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors

(2012) George V. Aslanidi et al.   VACCINE

Experimental gene transfer to the corneal endothelium

(2011) D. Kampik et al.   EXPERIMENTAL EYE RESEARCH

Ocular gene delivery using lentiviral vectors

(2011) K S Balaggan et al.   GENE THERAPY

Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

(2011) Dawn E Bowles et al.   MOLECULAR THERAPY

Gene therapy in the Cornea: 2005–present

(2011) Rajiv R. Mohan et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Mapping of the Disease Locus and Identification of ADAMTS10 As a Candidate Gene in a Canine Model of Primary Open Angle Glaucoma

(2011) John Kuchtey et al.   PLoS Genetics

AAV serotype influences gene transfer in corneal stroma in vivo

(2010) Ajay Sharma et al.   EXPERIMENTAL EYE RESEARCH

High-efficiency Transduction and Correction of Murine Hemophilia B Using AAV2 Vectors Devoid of Multiple Surface-exposed Tyrosines

(2010) David M Markusic et al.   MOLECULAR THERAPY

Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells

(2009) Benjamin Junglas et al.   EXPERIMENTAL EYE RESEARCH

The trabecular meshwork outflow pathways: Structural and functional aspects

(2009) Ernst R. Tamm   EXPERIMENTAL EYE RESEARCH

Prostaglandin Pathway Gene Therapy for Sustained Reduction of Intraocular Pressure

(2009) Román A Barraza et al.   MOLECULAR THERAPY

Corneal dystrophies

(2009) Gordon K Klintworth   Orphanet Journal of Rare Diseases

A Novel Adeno-Associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells

(2009) Ryan R. Klimczak et al.   PLoS One

Extracellular matrix in the trabecular meshwork

(2008) Ted S. Acott et al.   EXPERIMENTAL EYE RESEARCH

Structural changes of the trabecular meshwork in different kinds of glaucoma

(2008) Ozan-Yüksel Tektas et al.   EXPERIMENTAL EYE RESEARCH

Novel AAV serotypes for improved ocular gene transfer

(2008) Corinna Lebherz et al.   JOURNAL OF GENE MEDICINE

Self-complementary AAV Vectors; Advances and Applications

(2008) Douglas M McCarty   MOLECULAR THERAPY

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

(2008) Albert M. Maguire et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

(2008) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

(2008) L. Zhong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

(2008) A. V. Cideciyan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA