UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression

UPR-mediated TRIB3 expression correlates with reduced AKT phosphorylation and inability of interleukin 6 to overcome palmitate-induced apoptosis in RINm5F cells

(2010) José Edgar Nicoletti-Carvalho et al.   JOURNAL OF ENDOCRINOLOGY

Smad5 regulates Akt2 expression and insulin-induced glucose uptake in L6 myotubes

(2010) Fernando F. Anhê et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

(2009) Sung Hoon Back et al.   Cell Metabolism

Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice

(2009) M. S. Han et al.   DIABETES

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload

(2009) A. M. Preston et al.   DIABETOLOGIA

Expansion of β-cell mass in response to pregnancy

(2009) Sebastian Rieck et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hyperglycemia Induces Apoptosis of Human Pancreatic Islet Endothelial Cells

(2008) Enrica Favaro et al.   AMERICAN JOURNAL OF PATHOLOGY

Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR

(2008) Ying Cai et al.   BIOCHEMICAL PHARMACOLOGY

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS

The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

(2008) Donalyn Scheuner et al.   ENDOCRINE REVIEWS

Prolactin Receptor Is Required for Normal Glucose Homeostasis and Modulation of β-Cell Mass during Pregnancy

(2008) Carol Huang et al.   ENDOCRINOLOGY

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

TRIB3 is implicated in glucotoxicity- and oestrogen receptor-stress-induced β-cell apoptosis

(2008) Bo Qian et al.   JOURNAL OF ENDOCRINOLOGY