Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche

NOD/SCID-GAMMA Mice Are an Ideal Strain to Assess the Efficacy of Therapeutic Agents Used in the Treatment of Myeloma Bone Disease

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Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model

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Multiple myeloma: 2013 update on diagnosis, risk-stratification, and management

(2013) S. Vincent Rajkumar   AMERICAN JOURNAL OF HEMATOLOGY

Myeloid-Derived Suppressor Cells Regulate Growth of Multiple Myeloma by Inhibiting T Cells in Bone Marrow

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The Clinical Relevance of Cancer Cell Lines

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Characterization of a Novel Mouse Model of Multiple Myeloma and Its Use in Preclinical Therapeutic Assessment

(2013) Rosemary A. Fryer et al.   PLoS One

Patient-Specific 3D Microfluidic Tissue Model for Multiple Myeloma

(2013) Wenting Zhang et al.   TISSUE ENGINEERING PART C-METHODS

Evaluating cell lines as tumour models by comparison of genomic profiles

(2013) Silvia Domcke et al.   Nature Communications

Mechanical Strain Regulates Osteoblast Proliferation through Integrin-Mediated ERK Activation

(2012) Yu-xian Yan et al.   PLoS One

Myeloma cells inhibit osteogenic differentiation of mesenchymal stem cells and kill osteoblasts via TRAIL-induced apoptosis

(2011) Jinxiang Fu et al.   Archives of Medical Science

Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts

(2011) A Shiirevnyamba et al.   BRITISH JOURNAL OF CANCER

N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation

(2011) R. W. J. Groen et al.   HAEMATOLOGICA

Shear flow-induced formation of tubular cell protrusions in multiple myeloma cells

(2011) Ziv Porat et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A unique three-dimensional SCID-polymeric scaffold (SCID-synth-hu) model for in vivo expansion of human primary multiple myeloma cells

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Treatment of multiple myeloma

(2011) S. Vincent Rajkumar   Nature Reviews Clinical Oncology

Osteoblast function in myeloma

(2010) G. David Roodman   BONE

Abnormal bone turnover in monoclonal gammopathy of undetermined significance: analyses of type I collagen telopeptide, osteocalcin, bone-specific alkaline phosphatase and propeptides of type I and type III procollagens

(2010) T. Vejlgaard et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance

(2010) Hiroshi Tanaka et al.   NATURE MEDICINE

Cadherins as novel targets for anti-cancer therapy

(2009) Orest W. Blaschuk et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Osteogenic differentiation of mesenchymal stem cells in multiple myeloma: Identification of potential therapeutic targets

(2009) Nicola Giuliani et al.   EXPERIMENTAL HEMATOLOGY

The Mechanical Environment of Bone Marrow: A Review

(2008) Umut Atakan Gurkan et al.   ANNALS OF BIOMEDICAL ENGINEERING

A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma

(2008) J. Kirshner et al.   BLOOD

Genomic Changes and Gene Expression Profiles Reveal That Established Glioma Cell Lines Are Poorly Representative of Primary Human Gliomas

(2008) A. Li et al.   MOLECULAR CANCER RESEARCH