Detection of Innate Immune Response Modulating Impurities in Therapeutic Proteins
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Detection of Innate Immune Response Modulating Impurities in Therapeutic Proteins
Authors
Keywords
Endotoxins, Transcription factors, Immune response, Flagellin, Toll-like receptors, Antigens, Macrophages, Antigen-presenting cells
Journal
PLoS One
Volume 10, Issue 4, Pages e0125078
Publisher
Public Library of Science (PLoS)
Online
2015-04-23
DOI
10.1371/journal.pone.0125078
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Development of a cell system for siRNA screening of pathogen responses in human and mouse macrophages
- (2015) Ning Li et al. Scientific Reports
- AhR sensing of bacterial pigments regulates antibacterial defence
- (2014) Pedro Moura-Alves et al. NATURE
- TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7
- (2014) Chao-Yang Lai et al. VACCINE
- Evidence for the detection of non-endotoxin pyrogens by the whole blood monocyte activation test
- (2014) Nina Hasiwa ALTEX-Alternatives to Animal Experimentation
- Comparison of Limulus amebocyte lysate test methods for endotoxin measurement in protein solutions
- (2013) Lin Chen et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Scientific considerations in the review and approval of generic enoxaparin in the United States
- (2013) Sau Lee et al. NATURE BIOTECHNOLOGY
- Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination
- (2013) Nao Jounai et al. Frontiers in Cellular and Infection Microbiology
- Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy
- (2012) Narendra Chirmule et al. AAPS Journal
- Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation
- (2012) T. V. Brennan et al. BLOOD
- A bioassay for determination of lipopolysaccharide in environmental samples
- (2012) Marcus Peters et al. Innate Immunity
- Use of human MonoMac6 cells for development of in vitro assay predictive of adjuvant safety in vivo
- (2012) Marina Zaitseva et al. VACCINE
- Impact of Product-Related Factors on Immunogenicity of Biotherapeutics
- (2010) Satish Kumar Singh JOURNAL OF PHARMACEUTICAL SCIENCES
- Trace Levels of Innate Immune Response Modulating Impurities (IIRMIs) Synergize to Break Tolerance to Therapeutic Proteins
- (2010) Daniela Verthelyi et al. PLoS One
- Toll-like receptors and innate immunity
- (2009) Himanshu Kumar et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Innate immune control of nucleic acid-based vaccine immunogenicity
- (2009) Shohei Koyama et al. Expert Review of Vaccines
- Use of Toll-Like Receptor Assays To Detect and Identify Microbial Contaminants in Biological Products
- (2009) L.-Y. Huang et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Cytokine induction by pyrogens: Comparison of whole blood, mononuclear cells, and TLR-transfectants
- (2008) Robert Kikkert et al. JOURNAL OF IMMUNOLOGICAL METHODS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now