Genetic Fusions of a CFA/I/II/IV MEFA (Multiepitope Fusion Antigen) and a Toxoid Fusion of Heat-Stable Toxin (STa) and Heat-Labile Toxin (LT) of Enterotoxigenic Escherichia coli (ETEC) Retain Broad Anti-CFA and Antitoxin Antigenicity

Characterization of Immunological Cross-Reactivity between Enterotoxigenic Escherichia coli Heat-Stable Toxin and Human Guanylin and Uroguanylin

(2014) Arne M. Taxt et al.   INFECTION AND IMMUNITY

Characterization of Heat-Stable (STa) Toxoids of Enterotoxigenic Escherichia coli Fused to Double Mutant Heat-Labile Toxin Peptide in Inducing Neutralizing Anti-STa Antibodies

(2014) Xiaosai Ruan et al.   INFECTION AND IMMUNITY

Antigen-Specific Memory B-cell Responses to Enterotoxigenic Escherichia coli Infection in Bangladeshi Adults

(2014) Mohammad Murshid Alam et al.   PLoS Neglected Tropical Diseases

Multiepitope Fusion Antigen Induces Broadly Protective Antibodies That Prevent Adherence of Escherichia coli Strains Expressing Colonization Factor Antigen I (CFA/I), CFA/II, and CFA/IV

(2013) Xiaosai Ruan et al.   Clinical and Vaccine Immunology

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Toxicity and Immunogenicity of Enterotoxigenic Escherichia coli Heat-Labile and Heat-Stable Toxoid Fusion 3xSTaA14Q-LTS63K/R192G/L211A in a Murine Model

(2013) Chengxian Zhang et al.   PLoS One

Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid protein

(2013) A. Lundgren et al.   VACCINE

Oral immunization of a live attenuated Escherichia coli strain expressing a holotoxin-structured adhesin–toxoid fusion (1FaeG-FedF-LTA2:5LTB) protected young pigs against enterotoxigenic E. coli (ETEC) infection

(2013) Xiaosai Ruan et al.   VACCINE

Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant

(2013) J. Holmgren et al.   VACCINE

The Oral, Live Attenuated Enterotoxigenic Escherichia coli Vaccine ACE527 Reduces the Incidence and Severity of Diarrhea in a Human Challenge Model of Diarrheal Disease

(2012) Michael J. Darsley et al.   Clinical and Vaccine Immunology

Progress and hurdles in the development of vaccines against enterotoxigenicEscherichia coliin humans

(2012) Weiping Zhang et al.   Expert Review of Vaccines

Immune responses and protection in children in developing countries induced by oral vaccines

(2012) Firdausi Qadri et al.   VACCINE

A Tripartite Fusion, FaeG-FedF-LT192A2:B, of Enterotoxigenic Escherichia coli (ETEC) Elicits Antibodies That Neutralize Cholera Toxin, Inhibit Adherence of K88 (F4) and F18 Fimbriae, and Protect Pigs against K88ac/Heat-Labile Toxin Infection

(2011) Xiaosai Ruan et al.   Clinical and Vaccine Immunology

A Combination Vaccine Consisting of Three Live Attenuated Enterotoxigenic Escherichia coli Strains Expressing a Range of Colonization Factors and Heat-Labile Toxin Subunit B Is Well Tolerated and Immunogenic in a Placebo-Controlled Double-Blind Phase I Trial in Healthy Adults

(2011) Clayton Harro et al.   Clinical and Vaccine Immunology

Refinement of a Human Challenge Model for Evaluation of Enterotoxigenic Escherichia coli Vaccines

(2011) Clayton Harro et al.   Clinical and Vaccine Immunology

Heat-Labile- and Heat-Stable-Toxoid Fusions (LTR192G-STaP13F) of Human Enterotoxigenic Escherichia coli Elicit Neutralizing Antitoxin Antibodies

(2011) Mei Liu et al.   INFECTION AND IMMUNITY

A systematic review of ETEC epidemiology focusing on colonization factor and toxin expression

(2011) S.D. Isidean et al.   VACCINE

Heat-Stable Enterotoxin of Enterotoxigenic Escherichia coli as a Vaccine Target

(2010) A. Taxt et al.   INFECTION AND IMMUNITY

Global, regional, and national causes of child mortality in 2008: a systematic analysis

(2010) Robert E Black et al.   LANCET

Genetic Fusions of Heat-Labile (LT) and Heat-Stable (ST) Toxoids of Porcine Enterotoxigenic Escherichia coli Elicit Neutralizing Anti-LT and Anti-STa antibodies

(2009) W. Zhang et al.   INFECTION AND IMMUNITY

Vaccines against enterotoxigenicEscherichia coli

(2008) Ann-Mari Svennerholm et al.   Expert Review of Vaccines