TNFα Transport Induced by Dynamic Loading Alters Biomechanics of Intact Intervertebral Discs

Development and validation of a bioreactor system for dynamic loading and mechanical characterization of whole human intervertebral discs in organ culture

(2014) B.A. Walter et al.   JOURNAL OF BIOMECHANICS

A role for TNFα in intervertebral disc degeneration: A non-recoverable catabolic shift

(2013) D. Purmessur et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elastic, permeability and swelling properties of human intervertebral disc tissues: A benchmark for tissue engineering

(2013) Daniel H. Cortes et al.   JOURNAL OF BIOMECHANICS

Brain-derived neurotrophic factor is upregulated in the cervical dorsal root ganglia and spinal cord and contributes to the maintenance of pain from facet joint injury in the rat

(2013) Jeffrey V. Kras et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Role of cytokines in intervertebral disc degeneration: pain and disc content

(2013) Makarand V. Risbud et al.   Nature Reviews Rheumatology

Increased Interleukin-1α and Prostaglandin E2 Expression in the Spinal Cord at 1 Day After Painful Facet Joint Injury

(2013) Jeffrey V. Kras et al.   SPINE

An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes

(2013) Dessislava Z Markova et al.   ARTHRITIS RESEARCH & THERAPY

A complex interaction between Wnt signaling and TNF-α in nucleus pulposus cells

(2013) Akihiko Hiyama et al.   ARTHRITIS RESEARCH & THERAPY

Intervertebral disc degeneration: evidence for two distinct phenotypes

(2012) Michael A. Adams et al.   JOURNAL OF ANATOMY

The Prostaglandin E2 Receptor, EP2, Is Upregulated in the Dorsal Root Ganglion After Painful Cervical Facet Joint Injury in the Rat

(2012) Jeffrey V. Kras et al.   SPINE

The prevalence of MRI-defined spinal pathoanatomies and their association with Modic changes in individuals seeking care for low back pain

(2011) Hanne B. Albert et al.   EUROPEAN SPINE JOURNAL

The effects of dynamic loading on the intervertebral disc

(2011) Samantha C. W. Chan et al.   EUROPEAN SPINE JOURNAL

TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc

(2011) Jianru Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex loading affects intervertebral disc mechanics and biology

(2011) B.A. Walter et al.   OSTEOARTHRITIS AND CARTILAGE

An organ culture system to model early degenerative changes of the intervertebral disc

(2011) Ravi K Ponnappan et al.   ARTHRITIS RESEARCH & THERAPY

Enhancement of intervertebral disc cell senescence by WNT/β-catenin signaling-induced matrix metalloproteinase expression

(2010) Akihiko Hiyama et al.   ARTHRITIS AND RHEUMATISM

Validation of theoretical framework explaining active solute uptake in dynamically loaded porous media

(2010) Michael B. Albro et al.   JOURNAL OF BIOMECHANICS

MSC response to pH levels found in degenerating intervertebral discs

(2009) Karin Wuertz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanical Injury and Cytokines Cause Loss of Cartilage Integrity and Upregulate Proteins Associated with Catabolism, Immunity, Inflammation, and Repair

(2009) Anna L. Stevens et al.   MOLECULAR & CELLULAR PROTEOMICS

Upregulation of IL-6, IL-8 and CCL2 gene expression after acute inflammation: Correlation to clinical pain

(2009) Xiao-Min Wang et al.   PAIN

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration

(2009) S Jane Millward-Sadler et al.   ARTHRITIS RESEARCH & THERAPY

Effects of mechanical compression on metabolism and distribution of oxygen and lactate in intervertebral disc

(2008) Chun-Yuh Huang et al.   JOURNAL OF BIOMECHANICS

Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc

(2008) J. A. Hoyland et al.   RHEUMATOLOGY

Dynamic Compression Effects on Intervertebral Disc Mechanics and Biology

(2008) Casey L. Korecki et al.   SPINE