Identification of STAT1 and STAT3 Specific Inhibitors Using Comparative Virtual Screening and Docking Validation
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Title
Identification of STAT1 and STAT3 Specific Inhibitors Using Comparative Virtual Screening and Docking Validation
Authors
Keywords
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Journal
PLoS One
Volume 10, Issue 2, Pages e0116688
Publisher
Public Library of Science (PLoS)
Online
2015-02-25
DOI
10.1371/journal.pone.0116688
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- Antagonizing STAT3 Dimerization with a Rhodium(III) Complex
- (2014) Dik-Lung Ma et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Comparative screening and validation as a novel tool to identify STAT-specific inhibitors
- (2014) Małgorzata Szeląg et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2013) Mi-Jung Kim et al. CANCER LETTERS
- Fragment-based drug design and identification of HJC0123 , a novel orally bioavailable STAT3 inhibitor for cancer therapy
- (2013) Haijun Chen et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- In silico simulations of STAT1 and STAT3 inhibitors predict SH2 domain cross-binding specificity
- (2013) Malgorzata Szelag et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- STAT inhibitors for cancer therapy
- (2013) Muhammad Furqan et al. Journal of Hematology & Oncology
- MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0
- (2013) Koichiro Tamura et al. MOLECULAR BIOLOGY AND EVOLUTION
- Therapeutic modulators of STAT signalling for human diseases
- (2013) Gabriella Miklossy et al. NATURE REVIEWS DRUG DISCOVERY
- Role of STAT3 in Cancer Metastasis and Translational Advances
- (2013) Mohammad Zahid Kamran et al. Biomed Research International
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- Small Molecule Inhibitors of Signal Transducer and Activator of Transcription 3 (Stat3) Protein
- (2012) Bikash Debnath et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines
- (2012) Matthew A. Bill et al. PLoS One
- Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
- (2012) X. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Curcumin Induces the Differentiation of Myeloid-Derived Suppressor Cells and Inhibits Their Interaction with Cancer Cells and Related Tumor Growth
- (2011) S. P. Tu et al. Cancer Prevention Research
- STAT1 as a novel therapeutical target in pro-atherogenic signal integration of IFNγ, TLR4 and IL-6 in vascular disease
- (2011) Krzysztof Sikorski et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Resveratrol mitigates lipopolysaccharide- and Aβ-mediated microglial inflammation by inhibiting the TLR4/NF-κB/STAT signaling cascade
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- (2010) Matthew A Bill et al. Molecular Cancer
- Automated minimization of steric clashes in protein structures
- (2010) Srinivas Ramachandran et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Identification of a New Series of STAT3 Inhibitors by Virtual Screening
- (2010) Kenji Matsuno et al. ACS Medicinal Chemistry Letters
- Molecular dynamics simulations of the conformational changes in signal transducers and activators of transcription, Stat1 and Stat3
- (2009) Jianping Lin et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- SuperLooper--a prediction server for the modeling of loops in globular and membrane proteins
- (2009) P. W. Hildebrand et al. NUCLEIC ACIDS RESEARCH
- Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation
- (2009) Xuejun Xu et al. PLoS One
- Assessment of global and local model quality in CASP8 using Pcons and ProQ
- (2009) Per Larsson et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- MetaMQAP: A meta-server for the quality assessment of protein models
- (2008) Marcin Pawlowski et al. BMC BIOINFORMATICS
- Cryptotanshinone Inhibits Constitutive Signal Transducer and Activator of Transcription 3 Function through Blocking the Dimerization in DU145 Prostate Cancer Cells
- (2008) D.-S. Shin et al. CANCER RESEARCH
- Resveratrol addiction: To die or not to die
- (2008) Mehdi Shakibaei et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Profile-profile comparisons by COMPASS predict intricate homologies between protein families
- (2003) Ruslan I. Sadreyev et al. PROTEIN SCIENCE
- A normalized root-mean-spuare distance for comparing protein three-dimensional structures
- (2002) Oliviero Carugo et al. PROTEIN SCIENCE
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