A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)

Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation

(2014) S.-H. Yi et al.   DEVELOPMENT

Abrogation of  -synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats

(2014) J. P. L. Daher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1 −/− mice

(2013) Thi A Nguyen et al.   Journal of Neuroinflammation

NURR1 in Parkinson disease—from pathogenesis to therapeutic potential

(2013) Mickael Decressac et al.   Nature Reviews Neurology

Maternal inflammation promotes fetal microglial activation and increased cholinergic expression in the fetal basal forebrain: role of interleukin-6

(2013) Lorelei Pratt et al.   PEDIATRIC RESEARCH

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

(2013) B. Kadkhodaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Markers of Inflammation in Traumatic Brain Injury

(2013) Thomas Woodcock et al.   Frontiers in Neurology

Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity

(2012) F. Gillardon et al.   NEUROSCIENCE

Viral and Inflammatory Triggers of Neurodegenerative Diseases

(2012) M. Deleidi et al.   Science Translational Medicine

 -Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons

(2012) M. Decressac et al.   Science Translational Medicine

The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation

(2011) Yvonne Couch et al.   Journal of Neuroinflammation

Age-related changes in dopamine signaling in Nurr1 deficient mice as a model of Parkinson's disease

(2011) Lifen Zhang et al.   NEUROBIOLOGY OF AGING

Role of Interleukin 6 and Alpha-Globulins in Differentiating Alzheimer and Vascular Dementias

(2011) Azza A. Helmy et al.   Neurodegenerative Diseases

Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration

(2010) Robert Field et al.   BRAIN BEHAVIOR AND IMMUNITY

Expressions and possible roles of GDNF receptors in the developing dopaminergic neurons

(2010) Jun Ping Cao et al.   BRAIN RESEARCH BULLETIN

The Toll-Like Receptor-3 Agonist Polyinosinic:Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration

(2010) M. Deleidi et al.   JOURNAL OF NEUROSCIENCE

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV  -Synucleinopathy

(2009) C. Y. Chung et al.   JOURNAL OF NEUROSCIENCE

Peripheral challenge with double-stranded RNA elicits global up-regulation of cytokine gene expression in the brain

(2009) Gregory W. Konat et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Distinct neuroinflammatory profile in post-mortem human Huntingtonʼs disease

(2009) Aurelio Silvestroni et al.   NEUROREPORT

Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease

(2008) James B Koprich et al.   Journal of Neuroinflammation

Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration

(2008) T. C. Frank-Cannon et al.   JOURNAL OF NEUROSCIENCE

Inflammatory priming of the substantia nigra influences the impact of later paraquat exposure: Neuroimmune sensitization of neurodegeneration

(2008) Emily N. Mangano et al.   NEUROBIOLOGY OF AGING