Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS?

Signaling through MyD88 Regulates Leukocyte Recruitment after Brain Injury

(2014) A. A. Babcock et al.   JOURNAL OF IMMUNOLOGY

Dual Signaling of MyD88 and TRIF Is Critical for Maximal TLR4-Induced Dendritic Cell Maturation

(2014) H. Shen et al.   JOURNAL OF IMMUNOLOGY

TLR Ligands in the Local Treatment of Established Intracerebral Murine Gliomas

(2014) O. M. Grauer et al.   JOURNAL OF IMMUNOLOGY

Peptides Targeting Toll-Like Receptor Signalling Pathways for Novel Immune Therapeutics

(2010) Rosa Gomariz et al.   CURRENT PHARMACEUTICAL DESIGN

Neuronal caspase-3 and PARP-1 correlate differentially with apoptosis and necrosis in ischemic human stroke

(2009) Tiina Sairanen et al.   ACTA NEUROPATHOLOGICA

Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat

(2009) Aida Maddahi et al.   BMC NEUROSCIENCE

Brain dendritic cells in ischemic stroke: Time course, activation state, and origin

(2009) Jennifer C. Felger et al.   BRAIN BEHAVIOR AND IMMUNITY

Delayed post ischemic treatment with Rosiglitazone attenuates infarct volume, neurological deficits and neutrophilia after embolic stroke in rat

(2009) Mohammad Allahtavakoli et al.   BRAIN RESEARCH

Oxidative Stress-Induced Necrotic Cell Death via Mitochondira-Dependent Burst of Reactive Oxygen Species

(2009) Kyungsun Choi et al.   CURRENT NEUROVASCULAR RESEARCH

Effects of G-CSF treatment on neutrophil mobilization and neurological outcome after transient focal ischemia

(2009) Jan-Kolja Strecker et al.   EXPERIMENTAL NEUROLOGY

Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

(2009) K. L. Lambertsen et al.   JOURNAL OF NEUROSCIENCE

Changes in risk factors and preventive treatments by stroke subtypes over 20years: A population-based study

(2009) Yannick Béjot et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

CNS Immune Responses Following Experimental Stroke

(2009) Dannielle Zierath et al.   Neurocritical Care

Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice

(2009) M. Schilling et al.   NEUROSCIENCE

Acute in vivo exposure to interferon-  enables resident brain dendritic cells to become effective antigen presenting cells

(2009) A. Gottfried-Blackmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Scope of Preclinical Testing Versus Quality Control Within Experiments

(2009) Victoria E. O'Collins et al.   STROKE

The Spectrum of Systemic Immune Alterations After Murine Focal Ischemia

(2009) Arthur Liesz et al.   STROKE

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Blood Brain Barrier in Hypoxic-Ischemic Conditions

(2008) C. Kaur et al.   CURRENT NEUROVASCULAR RESEARCH

Interleukin-10 inhibits tumor necrosis factor-α production in lipopolysaccharide-stimulated RAW 264.7 cells through reduced MyD88 expression

(2008) Jargalsaikhan Dagvadorj et al.   Innate Immunity

The Crystal Structure of the Human Toll-like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer

(2008) Tomas Nyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue Inhibitor of Metalloproteinases Protect Blood—Brain Barrier Disruption in Focal Cerebral Ischemia

(2008) Motoaki Fujimoto et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Toll-Like Receptor 9: A New Target of Ischemic Preconditioning in the Brain

(2008) Susan L Stevens et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release

(2008) Eloy Cuadrado et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury

(2008) Fang Hua et al.   JOURNAL OF NEUROIMMUNOLOGY

Focal cerebral ischemia in the TNFalpha-transgenic rat

(2008) L Creed Pettigrew et al.   Journal of Neuroinflammation

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

(2008) Bettina H Clausen et al.   Journal of Neuroinflammation

Expansion and evolution of cell death programmes

(2008) Alexei Degterev et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration

(2008) Ulkan Kilic et al.   NEUROBIOLOGY OF DISEASE

Cell adhesion molecules and ischemic stroke

(2008) Gokhan Yilmaz et al.   NEUROLOGICAL RESEARCH

Toll-like receptor signaling in endogenous neuroprotection and stroke

(2008) B.J. Marsh et al.   NEUROSCIENCE

Microglial activation and TNF  production mediate altered CNS excitability following peripheral inflammation

(2008) K. Riazi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

(2008) L. Liu et al.   SCIENCE

Ischemic Postconditioning Inhibits Apoptosis After Focal Cerebral Ischemia/Reperfusion Injury in the Rat

(2008) Bianzhi Xing et al.   STROKE

Induction of Immunologic Tolerance to Myelin Basic Protein Prevents Central Nervous System Autoimmunity and Improves Outcome After Stroke

(2008) J. Michael Gee et al.   STROKE

Methodological Quality of Animal Studies of Neuroprotective Agents Currently in Phase II/III Acute Ischemic Stroke Trials

(2008) Maria Philip et al.   STROKE

Early Neutrophilia Is Associated With Volume of Ischemic Tissue in Acute Stroke

(2007) Brian H. Buck et al.   STROKE