Phospho-Aspirin-2 (MDC-22) Inhibits Estrogen Receptor Positive Breast Cancer Growth Both In Vitro and In Vivo by a Redox-Dependent Effect

Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress

(2014) Liqun Huang et al.   BMC CANCER

Oxidative stress-induced p53 activity is enhanced by a redox-sensitive TP53INP1 SUMOylation

(2014) S Peuget et al.   CELL DEATH AND DIFFERENTIATION

Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer

(2013) Enric Domingo et al.   JOURNAL OF CLINICAL ONCOLOGY

Aerosol Administration of Phospho-Sulindac Inhibits Lung Tumorigenesis

(2013) K. W. Cheng et al.   MOLECULAR CANCER THERAPEUTICS

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer

(2013) Weiyi Toy et al.   NATURE GENETICS

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

(2012) Angelina V. Vaseva et al.   CELL

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

(2012) Sang-Min Jeon et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Aspirin Use, TumorPIK3CAMutation, and Colorectal-Cancer Survival

(2012) Xiaoyun Liao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phospho-Sulindac (OXT-328) Inhibits the Growth of Human Lung Cancer Xenografts in Mice: Enhanced Efficacy and Mitochondria Targeting by its Formulation in Solid Lipid Nanoparticles

(2012) Rongrong Zhu et al.   PHARMACEUTICAL RESEARCH

Phospho-ibuprofen (MDC-917) incorporated in nanocarriers: anti-cancer activity in vitro and in vivo

(2011) T Nie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress Mediates through Apoptosis the Anticancer Effect of Phospho-Nonsteroidal Anti-Inflammatory Drugs: Implications for the Role of Oxidative Stress in the Action of Anticancer Agents

(2011) Y. Sun et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats

(2010) L Huang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Aspirin Intake and Survival After Breast Cancer

(2010) Michelle D. Holmes et al.   JOURNAL OF CLINICAL ONCOLOGY

Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect

(2009) W. Zhao et al.   CARCINOGENESIS

F2-Isoprostanes in Human Health and Diseases: From Molecular Mechanisms to Clinical Implications

(2008) Samar Basu   ANTIOXIDANTS & REDOX SIGNALING

Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death

(2008) Yu Sun et al.   CARCINOGENESIS