Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Dmp1 Physically Interacts with p53 and Positively Regulates p53's Stability, Nuclear Localization, and Function

(2012) D. P. Frazier et al.   CANCER RESEARCH

The rebel angel: mutant p53 as the driving oncogene in breast cancer

(2012) D. Walerych et al.   CARCINOGENESIS

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Oxidative Stress Mediates through Apoptosis the Anticancer Effect of Phospho-Nonsteroidal Anti-Inflammatory Drugs: Implications for the Role of Oxidative Stress in the Action of Anticancer Agents

(2011) Y. Sun et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats

(2010) L Huang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Critical Roles of DMP1 in Human Epidermal Growth Factor Receptor 2/neu-Arf-p53 Signaling and Breast Cancer Development

(2010) P. Taneja et al.   CANCER RESEARCH

ADAM17 Regulates Epidermal Growth Factor Receptor Expression through the Activation of Notch1 in Non-Small Cell Lung Cancer

(2010) A. Baumgart et al.   CANCER RESEARCH

Phospho-Sulindac (OXT-328), a Novel Sulindac Derivative, Is Safe and Effective in Colon Cancer Prevention in Mice

(2010) Gerardo G. Mackenzie et al.   GASTROENTEROLOGY

A Novel Sulindac Derivative That Does Not Inhibit Cyclooxygenases but Potently Inhibits Colon Tumor Cell Growth and Induces Apoptosis with Antitumor Activity

(2009) G. A. Piazza et al.   Cancer Prevention Research

Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect

(2009) W. Zhao et al.   CARCINOGENESIS

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement

(2009) Jack Cuzick et al.   LANCET ONCOLOGY

Posttranslational Modification of p53: Cooperative Integrators of Function

(2009) D. W. Meek et al.   Cold Spring Harbor Perspectives in Biology

F2-Isoprostanes in Human Health and Diseases: From Molecular Mechanisms to Clinical Implications

(2008) Samar Basu   ANTIOXIDANTS & REDOX SIGNALING

The thioredoxin system: a key target in tumour and endothelial cells

(2008) A Mukherjee et al.   BRITISH JOURNAL OF RADIOLOGY

The Thioredoxin System Mediates Redox-Induced Cell Death in Human Colon Cancer Cells: Implications for the Mechanism of Action of Anticancer Agents

(2008) Y. Sun et al.   CANCER RESEARCH

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

The ADAM17–amphiregulin–EGFR Axis in Mammary Development and Cancer

(2008) Mark D. Sternlicht et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA