A Dynamic View of Molecular Switch Behavior at Serotonin Receptors: Implications for Functional Selectivity
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A Dynamic View of Molecular Switch Behavior at Serotonin Receptors: Implications for Functional Selectivity
Authors
Keywords
-
Journal
PLoS One
Volume 9, Issue 10, Pages e109312
Publisher
Public Library of Science (PLoS)
Online
2014-10-15
DOI
10.1371/journal.pone.0109312
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Dynamic Process of β2-Adrenergic Receptor Activation
- (2013) Rie Nygaard et al. CELL
- Recent developments in biased agonism
- (2013) James W Wisler et al. CURRENT OPINION IN CELL BIOLOGY
- Novel Insights into Biased Agonism at G Protein-Coupled Receptors and their Potential for Drug Design
- (2013) Maria Marti-Solano et al. CURRENT PHARMACEUTICAL DESIGN
- Activation of 5-hydroxytryptamine1B/1D/1Freceptors as a mechanism of action of antimigraine drugs
- (2013) Martha B Ramírez Rosas et al. EXPERT OPINION ON PHARMACOTHERAPY
- Conformational Flexibility and Structural Dynamics in GPCR-Mediated G Protein Activation: A Perspective
- (2013) Anita M. Preininger et al. JOURNAL OF MOLECULAR BIOLOGY
- Molecular signatures of G-protein-coupled receptors
- (2013) A. J. Venkatakrishnan et al. NATURE
- Signalling bias in new drug discovery: detection, quantification and therapeutic impact
- (2013) Terry Kenakin et al. NATURE REVIEWS DRUG DISCOVERY
- Structural Basis for Molecular Recognition at Serotonin Receptors
- (2013) C. Wang et al. SCIENCE
- Structural Features for Functional Selectivity at Serotonin Receptors
- (2013) D. Wacker et al. SCIENCE
- Structure-Function of the G Protein–Coupled Receptor Superfamily
- (2012) Vsevolod Katritch et al. Annual Review of Pharmacology and Toxicology
- Ensemble of G Protein-Coupled Receptor Active States
- (2012) P. S.-H. Park CURRENT MEDICINAL CHEMISTRY
- High-throughput molecular dynamics: the powerful new tool for drug discovery
- (2012) Matthew J. Harvey et al. DRUG DISCOVERY TODAY
- Structure and dynamics of the M3 muscarinic acetylcholine receptor
- (2012) Andrew C. Kruse et al. NATURE
- The Role of Water in Activation Mechanism of Human N-Formyl Peptide Receptor 1 (FPR1) Based on Molecular Dynamics Simulations
- (2012) Shuguang Yuan et al. PLoS One
- The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling
- (2012) Andreas Bock et al. Nature Communications
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- Activation mechanism of the 2-adrenergic receptor
- (2011) R. O. Dror et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathway and mechanism of drug binding to G-protein-coupled receptors
- (2011) Ron O. Dror et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discovery of -Arrestin-Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy
- (2011) J. A. Allen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of Orthosteric and Allosteric Site Mutations in M2Muscarinic Acetylcholine Receptors That Contribute to Ligand-selective Signaling Bias
- (2010) Karen J. Gregory et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Simulaid: A simulation facilitator and analysis program
- (2010) Mihaly Mezei JOURNAL OF COMPUTATIONAL CHEMISTRY
- Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery
- (2010) T. Kenakin et al. PHARMACOLOGICAL REVIEWS
- CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes
- (2009) Sunhwan Jo et al. BIOPHYSICAL JOURNAL
- ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time Scale
- (2009) M. J. Harvey et al. Journal of Chemical Theory and Computation
- Ligand binding and micro-switches in 7TM receptor structures
- (2009) Rie Nygaard et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Well-Tempered Metadynamics: A Smoothly Converging and Tunable Free-Energy Method
- (2008) Alessandro Barducci et al. PHYSICAL REVIEW LETTERS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search