Identification of Orthosteric and Allosteric Site Mutations in M2Muscarinic Acetylcholine Receptors That Contribute to Ligand-selective Signaling Bias

Orthosteric/Allosteric Bitopic Ligands: Going Hybrid at GPCRs

(2009) C. Valant et al.   MOLECULAR INTERVENTIONS

Characterization of a CNS penetrant, selective M1muscarinic receptor agonist, 77-LH-28-1

(2008) C J Langmead et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity

(2008) Johannes Antony et al.   FASEB JOURNAL

A Novel Mechanism of G Protein-coupled Receptor Functional Selectivity

(2008) Celine Valant et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Selective Allosteric Activator of the M1 Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats

(2008) C. K. Jones et al.   JOURNAL OF NEUROSCIENCE

Mutagenic Mapping Suggests a Novel Binding Mode for Selective Agonists of M1 Muscarinic Acetylcholine Receptors

(2008) G. Lebon et al.   MOLECULAR PHARMACOLOGY

New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)

(2008) V. Nawaratne et al.   MOLECULAR PHARMACOLOGY