Are mesenchymal stem cells in rheumatoid arthritis the good or bad guys?

Interaction of Mesenchymal Stem Cells with Fibroblast-like Synoviocytes via Cadherin-11 Promotes Angiogenesis by Enhanced Secretion of Placental Growth Factor

(2014) S.-J. Park et al.   JOURNAL OF IMMUNOLOGY

Intra-Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof-of-Concept Clinical Trial

(2014) Chris Hyunchul Jo et al.   STEM CELLS

Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells

(2014) Lluis Orozco et al.   TRANSPLANTATION

Injectable Cultured Bone Marrow–Derived Mesenchymal Stem Cells in Varus Knees With Cartilage Defects Undergoing High Tibial Osteotomy: A Prospective, Randomized Controlled Clinical Trial With 2 Years' Follow-up

(2013) Keng Lin Wong et al.   ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY

The influence of bone marrow- and synovium-derived mesenchymal stromal cells from osteoarthritis patients on regulatory T cells in co-culture

(2013) S. Hagmann et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

How Cytokine Networks Fuel Inflammation: Toward a cytokine-based disease taxonomy

(2013) Georg Schett et al.   NATURE MEDICINE

Mesenchymal stem cells in joint disease and repair

(2013) Frank Barry et al.   Nature Reviews Rheumatology

Cell-based approaches to joint surface repair: a research perspective

(2013) A.J. Roelofs et al.   OSTEOARTHRITIS AND CARTILAGE

Human Umbilical Cord Mesenchymal Stem Cell Therapy for Patients with Active Rheumatoid Arthritis: Safety and Efficacy

(2013) Liming Wang et al.   STEM CELLS AND DEVELOPMENT

Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells

(2013) Lluis Orozco et al.   TRANSPLANTATION

Interleukin-17A- or tumor necrosis factor α-mediated increase in proliferation of T cells cocultured with synovium-derived mesenchymal stem cells in rheumatoid arthritis

(2013) Zhengzheng Zhang et al.   ARTHRITIS RESEARCH & THERAPY

Bone marrow-derived and synovium-derived mesenchymal cells promote Th17 cell expansion and activation through caspase 1 activation: Contribution to the chronicity of rheumatoid arthritis

(2012) Assia Eljaafari et al.   ARTHRITIS AND RHEUMATISM

The role of stromal cells in the persistence of chronic inflammation

(2012) A. J. Naylor et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells

(2011) M. Bombardieri et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of mesenchymal stem cells in reestablishing immunologic tolerance in autoimmune rheumatic diseases

(2011) Gordon I. A. MacDonald et al.   ARTHRITIS AND RHEUMATISM

Functional mesenchymal stem cell niches in adult mouse knee joint synovium in vivo

(2011) Tobias B. Kurth et al.   ARTHRITIS AND RHEUMATISM

Mesenchymal stem cells and autoimmune diseases

(2011) Francesco Dazzi et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Allogeneic mesenchymal stem cells transplantation in patients with refractory RA

(2011) Jun Liang et al.   CLINICAL RHEUMATOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human single-chain variable fragment that specifically targets arthritic cartilage

(2010) Chris Hughes et al.   ARTHRITIS AND RHEUMATISM

Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture

(2010) Hans P. Kiener et al.   ARTHRITIS AND RHEUMATISM

Mesenchymal stem cells from development to postnatal joint homeostasis, aging, and disease

(2010) Cosimo De Bari et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Mesenchymal Stem Cells Inhibit Human Th17 Cell Differentiation and Function and Induce a T Regulatory Cell Phenotype

(2010) S. Ghannam et al.   JOURNAL OF IMMUNOLOGY

Safety of autologous bone marrow-derived mesenchymal stem cell transplantation for cartilage repair in 41 patients with 45 joints followed for up to 11 years and 5 months

(2010) Shigeyuki Wakitani et al.   Journal of Tissue Engineering and Regenerative Medicine

Mesenchymal stem cells in rheumatoid synovium: enumeration and functional assessment in relation to synovial inflammation level

(2009) E Jones et al.   ANNALS OF THE RHEUMATIC DISEASES

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

(2009) Stephanie Lefèvre et al.   NATURE MEDICINE

Distinct mesenchymal progenitor cell subsets in the adult human synovium

(2009) A. Karystinou et al.   RHEUMATOLOGY

Intra-articular Injected Synovial Stem Cells Differentiate into Meniscal Cells Directly and Promote Meniscal Regeneration Without Mobilization to Distant Organs in Rat Massive Meniscal Defect

(2009) Masafumi Horie et al.   STEM CELLS

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis

(2008) Eiki Koyama et al.   DEVELOPMENTAL BIOLOGY

Mesenchymal cells recruit and regulate T regulatory cells

(2008) M DIIANNI   EXPERIMENTAL HEMATOLOGY

A biomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells

(2007) Cosimo De Bari et al.   ARTHRITIS AND RHEUMATISM