Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells

Notochordal cell disappearance and modes of apoptotic cell death in a rat tail static compression-induced disc degeneration model

(2014) Takashi Yurube et al.   ARTHRITIS RESEARCH & THERAPY

Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice

(2013) Tokio Matsuzaki et al.   ANNALS OF THE RHEUMATIC DISEASES

The overexpression of SIRT1 inhibited osteoarthritic gene expression changes induced by interleukin-1β in human chondrocytes

(2012) Takehiko Matsushita et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Caspase 3 as a therapeutic target for regulation of intervertebral disc degeneration in rabbits

(2011) Hideki Sudo et al.   ARTHRITIS AND RHEUMATISM

Autophagy modulates osteoarthritis-related gene expression in human chondrocytes

(2011) Hiroshi Sasaki et al.   ARTHRITIS AND RHEUMATISM

Cell death pathology: Cross-talk with autophagy and its clinical implications

(2011) Ivano Amelio et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression of silent mating type information regulator 2 homolog 1 and its role in human intervertebral disc cell homeostasis

(2011) Zhongying Zhang et al.   ARTHRITIS RESEARCH & THERAPY

Autophagy in rat annulus fibrosus cells: evidence and possible implications

(2011) Chao Shen et al.   ARTHRITIS RESEARCH & THERAPY

Regulation of apoptosis in nucleus pulposus cells by optimized exogenous Bcl-2 overexpression

(2010) Hideki Sudo et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Plasma membrane contributes to the formation of pre-autophagosomal structures

(2010) Brinda Ravikumar et al.   NATURE CELL BIOLOGY

SIRT1 regulation of apoptosis of human chondrocytes

(2009) Koji Takayama et al.   ARTHRITIS AND RHEUMATISM

SIRT1: Regulation of longevity via autophagy

(2009) Antero Salminen et al.   CELLULAR SIGNALLING

Silent information regulator, Sirtuin 1, and age-related diseases

(2009) Li Zeng et al.   Geriatrics & Gerontology International

Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy

(2008) A. Apel et al.   CANCER RESEARCH

Aberrant Interaction between Parkinson Disease-associated Mutant UCH-L1 and the Lysosomal Receptor for Chaperone-mediated Autophagy

(2008) Tomohiro Kabuta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The influence of serum, glucose and oxygen on intervertebral disc cell growth in vitro: implications for degenerative disc disease

(2008) William E.B. Johnson et al.   ARTHRITIS RESEARCH & THERAPY