Sodium-Glucose Transporter-2 (SGLT2; SLC5A2) Enhances Cellular Uptake of Aminoglycosides

Repeated electroacupuncture attenuating of apelin expression and function in the rostral ventrolateral medulla in stress-induced hypertensive rats

(2013) Cheng-Rong Zhang et al.   BRAIN RESEARCH BULLETIN

Perivascular macrophage-like melanocyte responsiveness to acoustic trauma—a salient feature of strial barrier associated hearing loss

(2013) Fei Zhang et al.   FASEB JOURNAL

Integrity and Regeneration of Mechanotransduction Machinery Regulate Aminoglycoside Entry and Sensory Cell Death

(2013) Andrew A. Vu et al.   PLoS One

Identification of Cisplatin-Binding Proteins Using Agarose Conjugates of Platinum Compounds

(2013) Takatoshi Karasawa et al.   PLoS One

Elimination of Self-Reactive T Cells in the Thymus: A Timeline for Negative Selection

(2013) Ivan Lilyanov Dzhagalov et al.   PLOS BIOLOGY

Expression of Na+-d-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences

(2012) Ivan Sabolić et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Bumetanide Hyperpolarizes Madin–Darby Canine Kidney Cells and Enhances Cellular Gentamicin Uptake by Elevating Cytosolic Ca2+ Thus Facilitating Intermediate Conductance Ca2+-Activated Potassium Channels

(2012) Tian Wang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Effect of protamine on the accumulation of gentamicin in opossum kidney epithelial cells

(2012) Junya Nagai et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Orexin A regulates cardiovascular responses in stress-induced hypertensive rats

(2012) Fen Xiao et al.   NEUROPHARMACOLOGY

Nitric oxide modulates cardiovascular function in the rat by activating adenosine A2A receptors and inhibiting acetylcholine release in the rostral ventrolateral medulla

(2011) Mei-Yan Jiang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Dapagliflozin Versus Glipizide as Add-on Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control With Metformin: A randomized, 52-week, double-blind, active-controlled noninferiority trial

(2011) M. A. Nauck et al.   DIABETES CARE

Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects

(2011) S. Sha et al.   DIABETES OBESITY & METABOLISM

A Fluorescence Method for Measurement of Glucose Transport in Kidney Cells

(2011) Amy B. Blodgett et al.   Diabetes Technology & Therapeutics

Intracellular mechanisms of aminoglycoside-induced cytotoxicity

(2011) Takatoshi Karasawa et al.   Integrative Biology

TRPA1-Mediated Accumulation of Aminoglycosides in Mouse Cochlear Outer Hair Cells

(2011) Ruben S. Stepanyan et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Adenosine A2AR modulates cardiovascular function by activating ERK1/2 signal in the rostral ventrolateral medulla of acute myocardial ischemic rats

(2011) Meiyan Jiang et al.   LIFE SCIENCES

Decreased renal accumulation of aminoglycoside reflects defective receptor-mediated endocytosis in cystic fibrosis and Dent’s disease

(2011) Claudia Raggi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Acoustic Trauma Increases Cochlear and Hair Cell Uptake of Gentamicin

(2011) Hongzhe Li et al.   PLoS One

Functional Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity

(2011) Abdelrahman Alharazneh et al.   PLoS One

Calreticulin Binds to Gentamicin and Reduces Drug-Induced Ototoxicity

(2011) Takatoshi Karasawa et al.   TOXICOLOGICAL SCIENCES

Systemic aminoglycosides are trafficked via endolymph into cochlear hair cells

(2011) Hongzhe Li et al.   Scientific Reports

Discovery of Canagliflozin, a NovelC-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus(1)

(2010) Sumihiro Nomura et al.   JOURNAL OF MEDICINAL CHEMISTRY

Familial Renal Glucosuria and SGLT2: From a Mendelian Trait to a Therapeutic Target

(2009) R. Santer et al.   Clinical Journal of the American Society of Nephrology

Trafficking of Systemic Fluorescent Gentamicin into the Cochlea and Hair Cells

(2009) Qi Wang et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Reanalysis of structure/function correlations in the region of transmembrane segments 4 and 5 of the rabbit sodium/glucose cotransporter

(2008) Tiemin Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Osmotic Water Transport with Glucose in GLUT2 and SGLT

(2008) Richard J. Naftalin   BIOPHYSICAL JOURNAL

Cellular localization of facilitated glucose transporter 1 (GLUT-1) in the cochlear stria vascularis: its possible contribution to the transcellular glucose pathway

(2008) Motonori Ando et al.   CELL AND TISSUE RESEARCH

Dapagliflozin, a Selective SGLT2 Inhibitor, Improves Glucose Homeostasis in Normal and Diabetic Rats

(2008) S. Han et al.   DIABETES

TRPV4 enhances the cellular uptake of aminoglycoside antibiotics

(2008) T. Karasawa et al.   JOURNAL OF CELL SCIENCE

TRPV4-Like Non-selective Cation Currents in Cultured Aortic Myocytes

(2008) Ryoichi Tanaka et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Remogliflozin Etabonate, in a Novel Category of Selective Low-Affinity Sodium Glucose Cotransporter (SGLT2) Inhibitors, Exhibits Antidiabetic Efficacy in Rodent Models

(2008) Y. Fujimori et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Communication Factor EDF and the Toxin–Antitoxin Module mazEF Determine the Mode of Action of Antibiotics

(2008) Ilana Kolodkin-Gal et al.   PLOS BIOLOGY

A systemic gentamicin pathway across the stria vascularis

(2007) Chun Fu Dai et al.   HEARING RESEARCH

Time dependent effects of gentamicin on the enzymes of carbohydrate metabolism, brush border membrane and oxidative stress in rat kidney tissues

(2007) Anees A. Banday et al.   LIFE SCIENCES