5-Lipoxygenase Inhibitors Attenuate TNF-α-Induced Inflammation in Human Synovial Fibroblasts

5-Lipoxygenase plays a pivotal role in endothelial adhesion of monocytes via an increased expression of Mac-1

(2013) Seung Jin Lee et al.   CARDIOVASCULAR RESEARCH

Statins Inhibit Monocyte Chemotactic Protein 1 Expression in Endometriosis

(2012) Hakan Cakmak et al.   Reproductive Sciences

15-deoxy-Δ12,14-prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts

(2011) Tzu-Hung Lin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression

(2011) Carlos H. Serezani et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes

(2011) L. Philippe et al.   JOURNAL OF IMMUNOLOGY

Hypoxia But Not Inflammation Augments Glucose Uptake in Human Macrophages

(2011) Eduardo J. Folco et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Zileuton Reduces Inflammatory Reaction and Brain Damage Following Permanent Cerebral Ischemia in Rats

(2010) Xian-kun Tu et al.   INFLAMMATION

Rheumatoid arthritis progression mediated by activated synovial fibroblasts

(2010) Elena Neumann et al.   TRENDS IN MOLECULAR MEDICINE

Risk of incident or recurrent malignancies among patients with rheumatoid arthritis exposed to biologic therapy in the German biologics register RABBIT

(2010) Anja Strangfeld et al.   ARTHRITIS RESEARCH & THERAPY

Drug-specific risk of tuberculosis in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register (BSRBR)

(2009) W. G. Dixon et al.   ANNALS OF THE RHEUMATIC DISEASES

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Combination therapies that inhibit cyclooxygenase-2 and leukotriene synthesis prevent disease in murine collagen induced arthritis

(2009) G. D. Anderson et al.   INFLAMMATION RESEARCH

Prostaglandin E2 Differentially Modulates Proinflammatory/Prodestructive Effects of TNF-  on Synovial Fibroblasts via Specific E Prostanoid Receptors/cAMP

(2009) E. Kunisch et al.   JOURNAL OF IMMUNOLOGY

Regulation of TNFα and IL1β in rheumatoid arthritis synovial fibroblasts by leukotriene B4

(2009) Shaohua Xu et al.   RHEUMATOLOGY INTERNATIONAL

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

(2009) Karina Roxana Gheorghe et al.   ARTHRITIS RESEARCH & THERAPY

Leukotriene B4 enhances the activity of nuclear factor- B pathway through BLT1 and BLT2 receptors in atherosclerosis

(2008) E. Sanchez-Galan et al.   CARDIOVASCULAR RESEARCH

Regulation of pro-inflammatory responses by lipoxygenases via intracellular reactive oxygen species in vitro and in vivo

(2008) So Yong Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis

(2008) Erika H. Noss et al.   IMMUNOLOGICAL REVIEWS

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION