Role of the DNA Base Excision Repair Protein, APE1 in Cisplatin, Oxaliplatin, or Carboplatin Induced Sensory Neuropathy

Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline

(2014) Dawn L. Hershman et al.   JOURNAL OF CLINICAL ONCOLOGY

Inhibition of Apurinic/Apyrimidinic Endonuclease I’s Redox Activity Revisited

(2013) Jun Zhang et al.   BIOCHEMISTRY

DNA damage response in peripheral nervous system: Coping with cancer therapy-induced DNA lesions

(2013) Ella W. Englander   DNA REPAIR

Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity

(2013) Anbarasi Kothandapani et al.   NUCLEIC ACIDS RESEARCH

Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors

(2012) Rebeka Sultana et al.   INTERNATIONAL JOURNAL OF CANCER

Characterization of the Redox Activity and Disulfide Bond Formation in Apurinic/Apyrimidinic Endonuclease

(2011) Meihua Luo et al.   BIOCHEMISTRY

Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines

(2011) M Z Mohammed et al.   BRITISH JOURNAL OF CANCER

Prolonged Oxaliplatin Exposure Alters Intracellular Calcium Signaling: A New Mechanism to Explain Oxaliplatin-Associated Peripheral Neuropathy

(2011) Christin Schulze et al.   Clinical Colorectal Cancer

The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation

(2011) Michael R. Vasko et al.   DNA REPAIR

Functional deficits in peripheral nerve mitochondria in rats with paclitaxel- and oxaliplatin-evoked painful peripheral neuropathy

(2011) Huaien Zheng et al.   EXPERIMENTAL NEUROLOGY

Impact of APE1/Ref-1 Redox Inhibition on Pancreatic Tumor Growth

(2011) M. L. Fishel et al.   MOLECULAR CANCER THERAPEUTICS

Platinum-Based Compounds and Risk for Cardiovascular Toxicity in the Elderly: Role of the Antioxidants in Chemoprevention

(2011) Patrizia Ferroni et al.   REJUVENATION RESEARCH

APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1

(2011) Mark R. Kelley et al.   Current Molecular Pharmacology

Reduced Expression of DNA Repair and Redox Signaling Protein APE1/Ref-1 Impairs Human Pancreatic Cancer Cell Survival, Proliferation, and Cell Cycle Progression

(2010) Yanlin Jiang et al.   CANCER INVESTIGATION

Peroxiredoxin 6 Overexpression Attenuates Cisplatin-Induced Apoptosis in Human Ovarian Cancer Cells

(2010) Jhang Ho Pak et al.   CANCER INVESTIGATION

The Role of Oxidative Stress and Anti-Oxidant Treatment in Platinum-Induced Peripheral Neurotoxicity

(2010) V. A. Carozzi et al.   CURRENT CANCER DRUG TARGETS

Design and Synthesis of Novel Quinone Inhibitors Targeted to the Redox Function of Apurinic/Apyrimidinic Endonuclease 1/Redox Enhancing Factor-1 (Ape1/Ref-1)

(2010) Rodney L. Nyland et al.   JOURNAL OF MEDICINAL CHEMISTRY

Roles of NADPH Oxidases in Cisplatin-Induced Reactive Oxygen Species Generation and Ototoxicity

(2010) H.-J. Kim et al.   JOURNAL OF NEUROSCIENCE

Novel Small-Molecule Inhibitor of Apurinic/Apyrimidinic Endonuclease 1 Blocks Proliferation and Reduces Viability of Glioblastoma Cells

(2010) A. Bapat et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Chemotherapy-induced peripheral neurotoxicity

(2010) Guido Cavaletti et al.   Nature Reviews Neurology

Vasodilatation in the rat dorsal hindpaw induced by activation of sensory neurons is reduced by paclitaxel

(2010) N.G. Gracias et al.   NEUROTOXICOLOGY

Intraepidermal nerve fiber loss corresponds to the development of Taxol-induced hyperalgesia and can be prevented by treatment with minocycline

(2010) J. Boyette-Davis et al.   PAIN

Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: Use of APE1 small molecule inhibitors to delineate APE1 functions

(2009) Yanlin Jiang et al.   DNA REPAIR

Inhibition of transcription by platinum antitumor compounds

(2009) Ryan C. Todd et al.   Metallomics

Platinum neurotoxicity pharmacogenetics

(2009) S. R. McWhinney et al.   MOLECULAR CANCER THERAPEUTICS

Going Ape as an Approach to Cancer Therapeutics

(2008) Aditi Bapat et al.   ANTIOXIDANTS & REDOX SIGNALING

The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme

(2008) Gianluca Tell et al.   ANTIOXIDANTS & REDOX SIGNALING

Implications of Apurinic/Apyrimidinic Endonuclease in Reactive Oxygen Signaling Response after Cisplatin Treatment of Dorsal Root Ganglion Neurons

(2008) Y. Jiang et al.   CANCER RESEARCH

Chemotherapy-induced neuropathy

(2008) Anthony J. Windebank et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM