Fucoidan Induces Cancer Cell Apoptosis by Modulating the Endoplasmic Reticulum Stress Cascades

The eIF2α kinases: their structures and functions

(2013) Neysan Donnelly et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78

(2013) Mehdi Hammadi et al.   FASEB JOURNAL

Brown seaweed fucoidan: Biological activity and apoptosis, growth signaling mechanism in cancer

(2013) Kalimuthu Senthilkumar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fucoidans as Potential Inhibitors of HIV-1

(2013) Maria Prokofjeva et al.   Marine Drugs

Fucoidan Extract Enhances the Anti-Cancer Activity of Chemotherapeutic Agents in MDA-MB-231 and MCF-7 Breast Cancer Cells

(2013) Zhongyuan Zhang et al.   Marine Drugs

Structural Characteristics and Anticancer Activity of Fucoidan from the Brown Alga Sargassum mcclurei

(2013) Pham Thinh et al.   Marine Drugs

Induction of Apoptosis by Fucoidan in Human Leukemia U937 Cells through Activation of p38 MAPK and Modulation of Bcl-2 Family

(2013) Hyun Park et al.   Marine Drugs

The Anticancer Effect of Fucoidan in PC-3 Prostate Cancer Cells

(2013) Hye-Jin Boo et al.   Marine Drugs

Fucoidan Inhibited 4T1 Mouse Breast Cancer Cell Growth In Vivo and In Vitro Via Downregulation of Wnt/β-Catenin Signaling

(2013) Meilan Xue et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Fucoidan induces changes in the epithelial to mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGF  receptor degradation in breast cancer

(2012) H.-Y. Hsu et al.   CARCINOGENESIS

Endoplasmic reticulum protein 29 regulates epithelial cell integrity during the mesenchymal–epithelial transition in breast cancer cells

(2012) I F Bambang et al.   ONCOGENE

Anticancer Properties and Mechanisms of Fucoidan on Mouse Breast Cancer In Vitro and In Vivo

(2012) Meilan Xue et al.   PLoS One

Fucoidan from Seaweed Fucus vesiculosus Inhibits Migration and Invasion of Human Lung Cancer Cell via PI3K-Akt-mTOR Pathways

(2012) Hyunkyoung Lee et al.   PLoS One

Salubrinal, an eIF2α dephosphorylation inhibitor, enhances cisplatin-induced oxidative stress and nephrotoxicity in a mouse model

(2011) Cheng Tien Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antiproliferative Activity of Fucoidan Was Associated with the Induction of Apoptosis and Autophagy in AGS Human Gastric Cancer Cells

(2011) Hyun Soo Park et al.   JOURNAL OF FOOD SCIENCE

Inhibiting ERp29 expression enhances radiosensitivity in human nasopharyngeal carcinoma cell lines

(2011) Lin Qi et al.   MEDICAL ONCOLOGY

Fucoidan Extract Induces Apoptosis in MCF-7 Cells via a Mechanism Involving the ROS-Dependent JNK Activation and Mitochondria-Mediated Pathways

(2011) Zhongyuan Zhang et al.   PLoS One

Over-expression of ERp29 attenuates doxorubicin-induced cell apoptosis through up-regulation of Hsp27 in breast cancer cells

(2010) Daohai Zhang et al.   EXPERIMENTAL CELL RESEARCH

Roles of GRP78 in physiology and cancer

(2010) Lu-Hua Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inhibition of eIF2α Dephosphorylation Maximizes Bortezomib Efficiency and Eliminates Quiescent Multiple Myeloma Cells Surviving Proteasome Inhibitor Therapy

(2009) Denis M. Schewe et al.   CANCER RESEARCH

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibitory Effect of Fucoidan on Huh7 Hepatoma Cells Through Downregulation of CXCL12

(2009) Takeaki Nagamine et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Divergent Effects of PERK and IRE1 Signaling on Cell Viability

(2009) Jonathan H. Lin et al.   PLoS One

Toxicological Evaluation of Fucoidan from Cladosiphon okamuranus

(2008) T. Paul Gideon et al.   JOURNAL OF MEDICINAL FOOD

Fucoidan: Structure and Bioactivity

(2008) Bo Li et al.   MOLECULES

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY