Adaptive Human CDKAL1 Variants Underlie Hormonal Response Variations at the Enteroinsular Axis

Quantitative PCR Measurement of tRNA 2-Methylthio Modification for Assessing Type 2 Diabetes Risk

(2013) P. Xie et al.   CLINICAL CHEMISTRY

Alterations of Glucose-Dependent Insulinotropic Polypeptide and Expression of Genes Involved in Mammary Gland and Adipose Tissue Lipid Metabolism during Pregnancy and Lactation

(2013) R. Charlotte Moffett et al.   PLoS One

A Genome-Wide Association Study of Gestational Diabetes Mellitus in Korean Women

(2012) S. H. Kwak et al.   DIABETES

γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

(2012) J. Taneera et al.   DIABETOLOGIA

Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits

(2012) A. P. Gjesing et al.   DIABETOLOGIA

Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases

(2012) Rong Chen et al.   PLoS Genetics

The carriage of risk variants of CDKAL1 impairs beta-cell function in both diabetic and non-diabetic patients and reduces response to non-sulfonylurea and sulfonylurea agonists of the pancreatic KATP channel

(2011) Dimitry A. Chistiakov et al.   ACTA DIABETOLOGICA

Identification of Metabolic Modifiers That Underlie Phenotypic Variations in Energy-Balance Regulation

(2011) Chia Lin Chang et al.   DIABETES

Functional loss of Cdkal1, a novel tRNA modification enzyme, causes the development of type 2 diabetes [Review]

(2011) Fan-Yan Wei et al.   ENDOCRINE JOURNAL

Effects of GABAB receptor agonists and antagonists on glycemia regulation in mice

(2011) María M. Bonaventura et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

On Characterizing Adaptive Events Unique to Modern Humans

(2011) Jessica L. Crisci et al.   Genome Biology and Evolution

Deficit of tRNALys modification by Cdkal1 causes the development of type 2 diabetes in mice

(2011) Fan-Yan Wei et al.   JOURNAL OF CLINICAL INVESTIGATION

Association of Six Single Nucleotide Polymorphisms with Gestational Diabetes Mellitus in a Chinese Population

(2011) Ying Wang et al.   PLoS One

Association of a Cyclin-Dependent Kinase 5 Regulatory Subunit-Associated Protein 1-Like 1 (CDKAL1) Polymorphism With Elevated Hemoglobin A1c Levels and the Prevalence of Metabolic Syndrome in Japanese Men: Interaction With Dietary Energy Intake

(2010) K. Miyaki et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The Neutral Theory of Molecular Evolution in the Genomic Era

(2010) Masatoshi Nei et al.   Annual Review of Genomics and Human Genetics

Evolutionary Adaptations to Dietary Changes

(2010) F. Luca et al.   Annual Review of Nutrition

The Genetics of Human Adaptation: Hard Sweeps, Soft Sweeps, and Polygenic Adaptation

(2010) Jonathan K. Pritchard et al.   CURRENT BIOLOGY

 -Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic  -Cells

(2010) M. Braun et al.   DIABETES

CDKAL1 and type 2 diabetes: a global meta-analysis

(2010) M.A.S. Dehwah et al.   GENETICS AND MOLECULAR RESEARCH

Adaptive selection of an incretin gene in Eurasian populations

(2010) C. L. Chang et al.   GENOME RESEARCH

Deletion of CDKAL1 Affects Mitochondrial ATP Generation and First-Phase Insulin Exocytosis

(2010) Mica Ohara-Imaizumi et al.   PLoS One

Human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency

(2010) A. M. Hancock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kidney Disease Is Parasite-Slaying Protein's Downside

(2010) M. Leslie   SCIENCE

Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing

(2010) J. C. Roach et al.   SCIENCE

Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB Study

(2009) G H Goossens et al.   INTERNATIONAL JOURNAL OF OBESITY

Inferring the Joint Demographic History of Multiple Populations from Multidimensional SNP Frequency Data

(2009) Ryan N. Gutenkunst et al.   PLoS Genetics

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

SPSmart: adapting population based SNP genotype databases for fast and comprehensive web access

(2008) Jorge Amigo et al.   BMC BIOINFORMATICS

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion

(2008) K. Kirchhoff et al.   DIABETOLOGIA

Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population

(2008) Y. M. Cho et al.   DIABETOLOGIA

Association of the −243 A→G polymorphism of the glutamate decarboxylase 2 gene with obesity in girls with premature pubarche

(2008) Selma Feldman Witchel et al.   FERTILITY AND STERILITY

Single-Nucleotide Polymorphism rs7754840 ofCDKAL1Is Associated with Impaired Insulin Secretion in Nondiabetic Offspring of Type 2 Diabetic Subjects and in a Large Sample of Men with Normal Glucose Tolerance

(2008) Alena Stančáková et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Common Type 2 Diabetes Risk Gene Variants Associate with Gestational Diabetes

(2008) Jeannet Lauenborg et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

PGEToolbox: A Matlab Toolbox for Population Genetics and Evolution

(2008) J. J. Cai   JOURNAL OF HEREDITY