Deoxycytidine Kinase Augments ATM-Mediated DNA Repair and Contributes to Radiation Resistance

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

New insights into the synergism of nucleoside analogs with radiotherapy

(2013) Michael W Lee et al.   Radiation Oncology

Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress

(2012) Wayne R. Austin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage

(2012) Chunying Yang et al.   NUCLEIC ACIDS RESEARCH

DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells

(2012) Li Z. Luo et al.   PLoS One

Post-Translational Phosphorylation of Serine 74 of Human Deoxycytidine Kinase Favors the Enzyme Adopting the Open Conformation Making It Competent for Nucleoside Binding and Release

(2011) Saugata Hazra et al.   BIOCHEMISTRY

Beyond ATM: The protein kinase landscape of the DNA damage response

(2011) Ariel Bensimon et al.   FEBS LETTERS

Integrated Analysis of ATM Mediated Gene and Protein Expression Impacting Cellular Metabolism

(2011) Amrita K. Cheema et al.   JOURNAL OF PROTEOME RESEARCH

Deoxynucleoside Salvage Facilitates DNA Repair During Ribonucleotide Reductase Blockade in Human Cervical Cancers

(2011) Charles A. Kunos et al.   RADIATION RESEARCH

Enhanced susceptibility of T lymphocytes to oxidative stress in the absence of the cellular prion protein

(2010) Catherine Aude-Garcia et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

(2010) Claudia Cosentino et al.   EMBO JOURNAL

Novel PET Probes Specific for Deoxycytidine Kinase

(2010) C. J. Shu et al.   JOURNAL OF NUCLEAR MEDICINE

Enzymatic Regulation of Cytosolic Thymidine Kinase 1 and Mitochondrial Thymidine Kinase 2: A Mini Review

(2010) B. Munch-Petersen   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Requirement for deoxycytidine kinase in T and B lymphocyte development

(2010) G. Toy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribonucleotide Reductase Inhibition Enhances Chemoradiosensitivity of Human Cervical Cancers

(2010) Charles A. Kunos et al.   RADIATION RESEARCH

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Targeting the DNA Damage Response in Cancer

(2009) Mats Ljungman   CHEMICAL REVIEWS

Activity of ribonucleotide reductase helps determine how cells repair DNA double strand breaks

(2009) Martin D. Burkhalter et al.   DNA REPAIR

Increase in double-stranded DNA break-related foci in early-stage thymocytes of aged mice

(2009) J.E. Hesse et al.   EXPERIMENTAL GERONTOLOGY

Ribonucleotide reductase small subunit p53R2 suppresses MEK–ERK activity by binding to ERK kinase 2

(2009) C Piao et al.   ONCOGENE

Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography

(2009) Rachel E. Laing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues

(2008) Theresa McSorley et al.   FEBS LETTERS

Stem cells and aging in the hematopoietic system

(2008) Luigi A. Warren et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2′-deoxycytidine analog

(2008) Caius G Radu et al.   NATURE MEDICINE

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

(2008) Martin F. Lavin   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage

(2008) L. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA