(-)-Phenserine Attenuates Soman-Induced Neuropathology

Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: From ferroptosis to stroke

(2013) Rachel E. Speer et al.   FREE RADICAL BIOLOGY AND MEDICINE

MAP Kinase Phosphatase 1 (MKP-1/DUSP1) Is Neuroprotective in Huntington's Disease via Additive Effects of JNK and p38 Inhibition

(2013) D. M. Taylor et al.   JOURNAL OF NEUROSCIENCE

Syrian gas attack reinforces need for better anti-sarin drugs

(2013) Elie Dolgin   NATURE MEDICINE

Neurotrophic and Neuroprotective Actions of (−)- and (+)-Phenserine, Candidate Drugs for Alzheimer’s Disease

(2013) Anna M. Lilja et al.   PLoS One

Age-Dependent Neuroplasticity Mechanisms in Alzheimer Tg2576 Mice Following Modulation of Brain Amyloid-β Levels

(2013) Anna M. Lilja et al.   PLoS One

Fire in the ashes: Can failed Alzheimer’s disease drugs succeed with second chances?

(2012) Robert E. Becker et al.   Alzheimers & Dementia

Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival

(2012) Yan-Wei Tan et al.   BMC NEUROSCIENCE

A combination of [+] and [−]-Huperzine A improves protection against soman toxicity compared to [+]-Huperzine A in guinea pigs

(2012) Ying Wang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cyclic AMP Response Element Modulator-1 (CREM-1) Involves in Neuronal Apoptosis after Traumatic Brain Injury

(2012) Xinmin Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-β peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans

(2012) Maria L Maccecchini et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Alpha-linolenic acid is a potent neuroprotective agent against soman-induced neuropathology

(2012) Hongna Pan et al.   NEUROTOXICOLOGY

The anticholinergic and antiglutamatergic drug caramiphen reduces seizure duration in soman-exposed rats: Synergism with the benzodiazepine diazepam

(2012) M.K. Schultz et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cellular and Molecular Responses of Cultured Neurons to Stressful Stimuli

(2011) Jun Chen et al.   Dose-Response

Minimum effective drug concentrations of a transdermal patch system containing procyclidine and physostigmine for prophylaxis against soman poisoning in rhesus monkeys

(2011) Young Cho et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Increased expression of the chemokines CXCL1 and MIP-1α by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status epilepticus in rats

(2011) Erik A Johnson et al.   Journal of Neuroinflammation

Diet composition exacerbates or attenuates soman toxicity in rats: Implied metabolic control of nerve agent toxicity

(2011) Todd M. Myers et al.   NEUROTOXICOLOGY

Treatment efficacy in a soman-poisoned guinea pig model: added value of physostigmine?

(2010) Marloes J. A. Joosen et al.   ARCHIVES OF TOXICOLOGY

In vivo reactivation by oximes of inhibited blood, brain and peripheral tissue cholinesterase activity following exposure to nerve agents in guinea pigs

(2010) Tsung-Ming Shih et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Chronic exposure to the chemokine CCL3 enhances neuronal network activity in rat hippocampal cultures

(2010) M. Kuijpers et al.   JOURNAL OF NEUROIMMUNOLOGY

Gene Expression Profiling of Rat Hippocampus Following Exposure to the Acetylcholinesterase Inhibitor Soman

(2009) James F. Dillman et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Homer1 regulates the susceptibility to TRAIL

(2009) Jin Na Shin et al.   EXPERIMENTAL CELL RESEARCH

Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis

(2009) B. Fritsch et al.   NEUROSCIENCE

Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

(2009) Sheng-Jia Zhang et al.   PLoS Genetics

Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease

(2008) Ahmadul Kadir et al.   ANNALS OF NEUROLOGY

Effects of oximes on rate of decarbamylation of human red blood cell AChE measured with two different methods

(2008) Saskia Eckert et al.   BIOCHEMICAL PHARMACOLOGY

Identification of new Nerve Growth Factor-responsive immediate-early genes

(2008) T.F. Dijkmans et al.   BRAIN RESEARCH

Distinct Cellular Patterns of Upregulated Chemokine Expression Supporting a Prominent Inflammatory Role in Traumatic Brain Injury

(2008) Charlotte Israelsson et al.   JOURNAL OF NEUROTRAUMA

A Single in Vivo Application of Cholinesterase Inhibitors Has Neuron Type-Specific Effects on Nicotinic Receptor Activity in Guinea Pig Hippocampus

(2008) M. Alkondon et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Long-term cognitive deficits accompanied by reduced neurogenesis after soman poisoning

(2008) Marloes J.A. Joosen et al.   NEUROTOXICOLOGY

Hyperosmolar treatment of soman-induced brain lesions in mice: Evaluation of the effects through diffusion-weighted magnetic resonance imaging and through histology

(2008) Pierre Carpentier et al.   TOXICOLOGY

Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia

(2007) Jayne M. Ness et al.   JOURNAL OF NEUROSCIENCE RESEARCH