VASP Activation via the Gα13/RhoA/PKA Pathway Mediates Cucurbitacin-B-Induced Actin Aggregation and Cofilin-Actin Rod Formation

Formation of cofilin-actin rods following cucurbitacin-B-induced actin aggregation depends on slingshot homolog 1-mediated cofilin hyperactivation

(2013) Yan-Ting Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Effectiveness of Cucurbitacin B in BRCA1 Defective Breast Cancer Cells

(2013) Moltira Promkan et al.   PLoS One

Biological activities and potential molecular targets of cucurbitacins

(2012) Xiuping Chen et al.   ANTI-CANCER DRUGS

Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation

(2012) Shuai Ren et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cucurbitacin B Induces Cell Cycle Arrest, Apoptosis and Autophagy Associated with G Actin Reduction and Persistent Activation of Cofilin in Jurkat Cells

(2012) Jun-Shan Zhu et al.   PHARMACOLOGY

Cucurbitacin B induces rapid depletion of the G-actin pool through reactive oxygen species-dependent actin aggregation in melanoma cells

(2011) Y. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Phosphorylation of VASP by AMPK alters actin binding and occurs at a novel site

(2011) David M. Thomson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation

(2011) C Boykin et al.   BRITISH JOURNAL OF CANCER

Uncovering the intimate relationship between lipids, cholesterol and GPCR activation

(2011) Joanne Oates et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways

(2011) Ayako Kataoka et al.   Purinergic Signalling

Cucurbitacin E as a new inhibitor of cofilin phosphorylation in human leukemia U937 cells

(2010) Souichi Nakashima et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The effect of variations in phospholipid and sterol structure on the nature of lipid–sterol interactions in lipid bilayer model membranes

(2010) David A. Mannock et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Targeting of the actin cytoskeleton by insecticidal toxins from Photorhabdus luminescens

(2010) Alexander E. Lang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Cucurbitacin I Inhibits Cell Motility by Indirectly Interfering with Actin Dynamics

(2010) David A. Knecht et al.   PLoS One

Role of G12 proteins in oncogenesis and metastasis

(2009) Juhi Juneja et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562

(2009) Kin Tak Chan et al.   CANCER LETTERS

Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells

(2009) N. H. Thoennissen et al.   CANCER RESEARCH

Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells

(2009) Vivian W.Y. Lui et al.   CARCINOGENESIS

Differential VASP phosphorylation controls remodeling of the actin cytoskeleton

(2009) P. M. Benz et al.   JOURNAL OF CELL SCIENCE

Ena/VASP: towards resolving a pointed controversy at the barbed end

(2009) J. E. Bear et al.   JOURNAL OF CELL SCIENCE

Cucurbitacin B has a potent antiproliferative effect on breast cancer cellsin vitroandin vivo

(2008) Naoki Wakimoto et al.   CANCER SCIENCE

The function of G-protein coupled receptors and membrane cholesterol: specific or general interaction?

(2008) Yamuna Devi Paila et al.   GLYCOCONJUGATE JOURNAL

Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme

(2008) Dong Yin et al.   INTERNATIONAL JOURNAL OF CANCER

Cytoskeleton assembly at endothelial cell–cell contacts is regulated by αII-spectrin–VASP complexes

(2008) Peter M. Benz et al.   JOURNAL OF CELL BIOLOGY

Relaxing the actin cytoskeleton for adhesion and movement with Ena/VASP

(2008) Léa Trichet et al.   JOURNAL OF CELL BIOLOGY

Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells

(2008) Talin Haritunians et al.   LEUKEMIA RESEARCH