The Human Orphan Nuclear Receptor Tailless (TLX, NR2E1) Is Druggable
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Title
The Human Orphan Nuclear Receptor Tailless (TLX, NR2E1) Is Druggable
Authors
Keywords
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Journal
PLoS One
Volume 9, Issue 6, Pages e99440
Publisher
Public Library of Science (PLoS)
Online
2014-06-18
DOI
10.1371/journal.pone.0099440
References
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Related references
Note: Only part of the references are listed.- Structure-based Discovery of Antagonists of Nuclear Receptor LRH-1
- (2013) Cindy Benod et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- The Oncoprotein BCL11A Binds to Orphan Nuclear Receptor TLX and Potentiates its Transrepressive Function
- (2012) Sara B. Estruch et al. PLoS One
- Characterization of TLX Expression in Neural Stem Cells and Progenitor Cells in Adult Brains
- (2012) Shengxiu Li et al. PLoS One
- Nuclear receptors in stem cells and their therapeutic potential
- (2010) GuoQiang Sun et al. ADVANCED DRUG DELIVERY REVIEWS
- The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation
- (2010) H. K. Liu et al. GENES & DEVELOPMENT
- Nuclear Orphan Receptor TLX Induces Oct-3/4 for the Survival and Maintenance of Adult Hippocampal Progenitors upon Hypoxia
- (2010) Pavithra Lakshminarasimhan Chavali et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
- (2010) Jonathan B. Baell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Histone Demethylase LSD1 Regulates Neural Stem Cell Proliferation
- (2010) G. Sun et al. MOLECULAR AND CELLULAR BIOLOGY
- TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitors
- (2010) Muna Elmi et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells
- (2010) Hyo-Jung Park et al. MOLECULES AND CELLS
- Neural stem cells in the developing and adult brains
- (2009) Qiuhao Qu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures
- (2009) Guo-Zhong Li et al. PROTEOMICS
- Transrepressive Function of TLX Requires the Histone Demethylase LSD1
- (2008) A. Yokoyama et al. MOLECULAR AND CELLULAR BIOLOGY
- A role for adult TLX-positive neural stem cells in learning and behaviour
- (2008) Chun-Li Zhang et al. NATURE
- The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1
- (2008) E. P. Sablin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
- Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid–Activated Receptor
- (2008) Schoen W Kruse et al. PLOS BIOLOGY
- Neural stem cell self-renewal
- (2007) Yanhong Shi et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Structural determination of estrogen-related receptor γ in the presence of phenol derivative compounds
- (2007) Marta C. Abad et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Nuclear Receptor TLX Regulates Cell Cycle Progression in Neural Stem Cells of the Developing Brain
- (2007) Wenwu Li et al. MOLECULAR ENDOCRINOLOGY
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