The Effect of Antifibrotic Drugs in Rat Precision-Cut Fibrotic Liver Slices

Evolving therapies for liver fibrosis

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Precision-cut liver slices: A tool to model the liver ex vivo

(2013) Peter Olinga et al.   JOURNAL OF HEPATOLOGY

Therapy for Fibrotic Diseases: Nearing the Starting Line

(2013) S. L. Friedman et al.   Science Translational Medicine

Precision-cut liver slices as a model for the early onset of liver fibrosis to test antifibrotic drugs

(2013) Inge M. Westra et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Evaluation of fibrosis in precision-cut tissue slices

(2012) I. M. Westra et al.   XENOBIOTICA

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

Valproic acid administration for hepatic fibrosis: A balance between antifibrotic efficacy and hepatotoxicity

(2010) Yoshihiro Ikura et al.   HEPATOLOGY

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

(2010) Inge A M de Graaf et al.   Nature Protocols

Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cellsin vitroandin vivo

(2009) Inge Mannaerts et al.   HEPATOLOGY

Therapeutic targeting of the PDGF and TGF-β-signaling pathways in hepatic stellate cells by PTK787/ZK22258

(2009) Yuqing Liu et al.   LABORATORY INVESTIGATION

In vitro and in vivo antifibrotic effects of rosmarinic acid on experimental liver fibrosis

(2009) Gui-Sheng Li et al.   PHYTOMEDICINE

Potent antioxidant role of Pirfenidone in experimental cirrhosis

(2008) Adriana Salazar-Montes et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats

(2008) Marc Mejias et al.   HEPATOLOGY

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET