Brd4 Is Essential for IL-1β-Induced Inflammation in Human Airway Epithelial Cells

PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains

(2013) S. Picaud et al.   CANCER RESEARCH

Regulation of Wnt4 in chronic obstructive pulmonary disease

(2013) Andrew L. Durham et al.   FASEB JOURNAL

BET Protein Function Is Required for Inflammation: Brd2 Genetic Disruption and BET Inhibitor JQ1 Impair Mouse Macrophage Inflammatory Responses

(2013) A. C. Belkina et al.   JOURNAL OF IMMUNOLOGY

Airway inflammatory markers in chronic obstructive pulmonary disease patients and healthy smokers

(2013) SS Hacievliyagil et al.   Nigerian Journal of Clinical Practice

BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

(2012) C. J. Ott et al.   BLOOD

The bromodomain interaction module

(2012) Panagis Filippakopoulos et al.   FEBS LETTERS

Bromodomain-containing Protein 4 (BRD4) Regulates RNA Polymerase II Serine 2 Phosphorylation in Human CD4+ T Cells

(2012) Weishi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Molecular Bridge between RelA/p65 and NF-κB Target Genes via Histone Acetyltransferase TIP60 Cofactor

(2012) Jung-Woong Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of NF-κB Transcriptional Activity in HIV-associated Kidney Disease by BRD4 Inhibition

(2012) Guangtao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic mechanisms in neurological disease

(2012) Mira Jakovcevski et al.   NATURE MEDICINE

Chronic Obstructive Pulmonary Disease and Lung Cancer: A Lethal Association

(2011) Peter J. Barnes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Deletion of the Proline-Rich Region of the Murine Metastasis Susceptibility Gene Brd4 Promotes Epithelial-to-Mesenchymal Transition- and Stem Cell-Like Conversion

(2011) J. Alsarraj et al.   CANCER RESEARCH

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Differential patterns of histone acetylation in inflammatory bowel diseases

(2011) Loukia G Tsaprouni et al.   Journal of Inflammation-London

Aberrant epigenetic regulation of bromodomain Brd4 in human colon cancer

(2011) R. M. Rodriguez et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding

(2011) Simon C. Biddie et al.   MOLECULAR CELL

Targeting MYC dependence in cancer by inhibiting BET bromodomains

(2011) J. A. Mertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of oxidative stress in airways and lungs with reference to asthma and chronic obstructive pulmonary disease

(2010) K.F. Chung et al.   Annals of the New York Academy of Sciences

Acetylation of p65 at lysine 314 is important for late NF-κB-dependent gene expression

(2010) Karin M Rothgiesser et al.   BMC GENOMICS

Glucocorticosteroids: current and future directions

(2010) Peter J Barnes   BRITISH JOURNAL OF PHARMACOLOGY

Posttranslational modifications of NF-κB: Another layer of regulation for NF-κB signaling pathway

(2010) Bo Huang et al.   CELLULAR SIGNALLING

Inhibition of Inflammatory Cytokine Production from Rheumatoid Synovial Fibroblasts by a Novel I B Kinase Inhibitor

(2010) A. Tsuchiya et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Suppression of inflammation by a synthetic histone mimic

(2010) Edwige Nicodeme et al.   NATURE

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate

(2010) F Liu et al.   ONCOGENE

Chronic obstructive pulmonary disease: an update of treatment related to frequently associated comorbidities

(2010) Nicola J. Sinden et al.   Therapeutic Advances in Chronic Disease

Overcoming steroid unresponsiveness in airways disease: Figure 1

(2009) Ian M. Adcock et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neutrophil Elastase Represses IL-8/CXCL8 Synthesis in Human Airway Smooth Muscle Cells through Induction of NF- B Repressing Factor

(2009) S.-C. Ho et al.   JOURNAL OF IMMUNOLOGY

Oxidative Stress CausesIL8Promoter Hyperacetylation in Cystic Fibrosis Airway Cell Models

(2008) Toni R. Bartling et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Role of HDAC2 in the Pathophysiology of COPD

(2008) Peter J. Barnes   Annual Review of Physiology

Autoimmunity and oxidatively modified autoantigens

(2008) Biji T. Kurien et al.   AUTOIMMUNITY REVIEWS

Inflammatory Signaling and Aryl Hydrocarbon Receptor Mediate Synergistic Induction of Interleukin 6 in MCF-7 Cells

(2008) B. D. Hollingshead et al.   CANCER RESEARCH

Interleukin-6

(2008) Don D. Sin et al.   CHEST

Human hair follicles contain two forms of ATP-sensitive potassium channels, only one of which is sensitive to minoxidil

(2008) Katie Shorter et al.   FASEB JOURNAL

Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with cigarette smoke

(2008) Esmaeil Mortaz et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Brd4 Coactivates Transcriptional Activation of NF- B via Specific Binding to Acetylated RelA

(2008) B. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

CBP Is a Dosage-Dependent Regulator of Nuclear Factor-κB Suppression by the Estrogen Receptor

(2007) Kendall W. Nettles et al.   MOLECULAR ENDOCRINOLOGY

How corticosteroids control inflammation: Quintiles Prize Lecture 2005

(2006) Peter J Barnes   BRITISH JOURNAL OF PHARMACOLOGY