NF-Kappa B Modulation Is Involved in Celastrol Induced Human Multiple Myeloma Cell Apoptosis

Celastrol inhibits vasculogenesis by suppressing the VEGF-induced functional activity of bone marrow-derived endothelial progenitor cells

(2012) Shuai Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bortezomib induces heme oxygenase-1 expression in multiple myeloma

(2012) Lawrence N. Barrera et al.   CELL CYCLE

Interleukin 6 Signaling Regulates Promyelocytic Leukemia Protein Gene Expression in Human Normal and Cancer Cells

(2012) Sona Hubackova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibrils Colocalize Caspase-3 with Procaspase-3 to Foster Maturation

(2012) Julie A. Zorn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents

(2011) Kwong-Fai Wong et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Evidence that  -Secretase-Mediated Notch Signaling Induces Neuronal Cell Death via the Nuclear Factor- B-Bcl-2-Interacting Mediator of Cell Death Pathway in Ischemic Stroke

(2011) T. V. Arumugam et al.   MOLECULAR PHARMACOLOGY

Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1 

(2011) Y. Berda-Haddad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Celastrol: A New Therapeutic Potential of Traditional Chinese Medicine

(2010) T. Morita   AMERICAN JOURNAL OF HYPERTENSION

Celastrol: Molecular targets of Thunder God Vine

(2010) Antero Salminen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

(2010) Feng Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

(2010) Subash C. Gupta et al.   CANCER AND METASTASIS REVIEWS

Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer

(2010) Radhamani Kannaiyan et al.   CANCER LETTERS

Celastrol isolated from Tripterygium regelii induces apoptosis through both caspase-dependent and -independent pathways in human breast cancer cells

(2010) Hee-Sun Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor

(2010) Vivek R. Yadav et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

(2010) Daniel Paris et al.   Journal of Neuroinflammation

Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB

(2010) Yao Dai et al.   PLoS One

The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma

(2009) Di He et al.   BMC CANCER

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

(2009) B. B. Aggarwal et al.   CLINICAL CANCER RESEARCH

Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cellsin vitroand suppress experimental metastasisin vivo

(2009) Hiromichi Yamai et al.   INTERNATIONAL JOURNAL OF CANCER

Multiple myeloma

(2009) Marc S Raab et al.   LANCET

Proteasome inhibitors in the treatment of multiple myeloma

(2009) J J Shah et al.   LEUKEMIA

Celastrol Synergistically Enhances Temozolomide Cytotoxicity in Melanoma Cells

(2009) M. Chen et al.   MOLECULAR CANCER RESEARCH

Potential pharmacological control of the NF-κB pathway

(2009) Gautam Sethi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

NF- B as a Critical Link Between Inflammation and Cancer

(2009) M. Karin   Cold Spring Harbor Perspectives in Biology

HO-1 underlies resistance of AML cells to TNF-induced apoptosis

(2008) S. A. Rushworth et al.   BLOOD

Multiple myeloma

(2008) R. A. Kyle et al.   BLOOD

Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression

(2008) Yulun Huang et al.   CANCER LETTERS

Bortezomib in the front-line treatment of multiple myeloma

(2008) Paul G Richardson et al.   Expert Review of Anticancer Therapy