Inactivation of Bcl-2 through IκB kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE)

Modification of Akt2 by 4-Hydroxynonenal Inhibits Insulin-Dependent Akt Signaling in HepG2 Cells

(2011) C. T. Shearn et al.   BIOCHEMISTRY

Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors

(2011) Sora Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Image-based Screening Identifies Novel Roles for IκB Kinase and Glycogen Synthase Kinase 3 in Axonal Degeneration

(2011) Josiah Gerdts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional regulation of the Th17 immune response by IKKα

(2011) Li Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation

(2010) Renfang Mao et al.   CELLULAR SIGNALLING

IKK-dependent, NF-κB-independent control of autophagic gene expression

(2010) W C Comb et al.   ONCOGENE

Phenotypic High-Throughput Screening in Atherosclerosis Research: Focus on Macrophages

(2010) Anthony J. Muslin   Journal of Cardiovascular Translational Research

IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin

(2009) Ali Khoshnan et al.   PLoS One

Identification of Protein Targets of 4-Hydroxynonenal Using Click Chemistry for ex Vivo Biotinylation of Azido and Alkynyl Derivatives

(2008) Andrew Vila et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidized Low-Density Lipoproteins Trigger Endoplasmic Reticulum Stress in Vascular Cells

(2008) Marie Sanson et al.   CIRCULATION RESEARCH

Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells

(2008) Min-Jung Kim et al.   FEBS Journal

The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells

(2008) Young-Hee Kang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Global Analysis of Protein Damage by the Lipid Electrophile 4-Hydroxy-2-nonenal

(2008) Simona G. Codreanu et al.   MOLECULAR & CELLULAR PROTEOMICS

The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human B-cells is dependent on the mode of action of specific stresses

(2008) Donna E. Muscarella et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY