A Protoberberine Derivative HWY336 Selectively Inhibits MKK4 and MKK7 in Mammalian Cells: The Importance of Activation Loop on Selectivity

Antitumor effect of berberine against primary effusion lymphoma via inhibition of NF-κB pathway

(2012) Hiroki Goto et al.   CANCER SCIENCE

RAS/RAF/MEK Inhibitors in Oncology

(2012) M. Broggini   CURRENT MEDICINAL CHEMISTRY

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor

(2012) Lihong Wang et al.   PLoS One

Fully Activated MEK1 Exhibits Compromised Affinity for Binding of Allosteric Inhibitors U0126 and PD0325901

(2011) Payal R. Sheth et al.   BIOCHEMISTRY

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Automatic identification and representation of protein binding sites for molecular docking

(2010) Jim Ruppert et al.   PROTEIN SCIENCE

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL