Competition in Notch Signaling with Cis Enriches Cell Fate Decisions

A microRNA miR-34a-Regulated Bimodal Switch Targets Notch in Colon Cancer Stem Cells

(2013) Pengcheng Bu et al.   Cell Stem Cell

An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling

(2013) R. J. Fleming et al.   DEVELOPMENT

Lateral inhibition and neurogenesis: novel aspects in motion

(2013) Pau Formosa-Jordan et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Notch signaling at a glance

(2013) K. Hori et al.   JOURNAL OF CELL SCIENCE

A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells

(2013) S. Munoz Descalzo et al.   Molecular Systems Biology

Distinct TCR signaling pathways drive proliferation and cytokine production in T cells

(2013) Clifford S Guy et al.   NATURE IMMUNOLOGY

Discrete model of periodic pattern formation through a combined autocrine–juxtacrine cell signaling

(2013) David S A Simakov et al.   PHYSICAL BIOLOGY

Possible roles of DLK1 in the Notch pathway during development and disease

(2012) Farah A. Falix et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Different Cell Fates from Cell-Cell Interactions: Core Architectures of Two-Cell Bistable Networks

(2012) Hervé Rouault et al.   BIOPHYSICAL JOURNAL

Regulation of neuronal differentiation at the neurogenic wavefront

(2012) P. Formosa-Jordan et al.   DEVELOPMENT

Jagged1 and Notch1 help edit M cell patterning in Peyer’s patch follicle epithelium

(2012) En-Hui Hsieh et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Competition for Catalytic Resources Alters Biological Network Dynamics

(2012) Yannick Rondelez   PHYSICAL REVIEW LETTERS

A Mutation in EGF Repeat-8 of Notch Discriminates Between Serrate/Jagged and Delta Family Ligands

(2012) S. Yamamoto et al.   SCIENCE

Neural fate decisions mediated by trans-activation and cis-inhibition in Notch signaling

(2011) Ruiqi Wang et al.   BIOINFORMATICS

Cis–trans interactions of cell surface receptors: biological roles and structural basis

(2011) Werner Held et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanism and Significance of cis-Inhibition in Notch Signalling

(2011) David del Álamo et al.   CURRENT BIOLOGY

Robust selection of sensory organ precursors by the Notch–Delta pathway

(2011) Omer Barad et al.   CURRENT OPINION IN CELL BIOLOGY

From Notch signaling to fine-grained patterning: Modeling meets experiments

(2011) O Shaya et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Ral GTPase promotes asymmetric Notch activation in the Drosophila eye in response to Frizzled/PCP signaling by repressing ligand-independent receptor activation

(2011) Bomsoo Cho et al.   DEVELOPMENT

Notch signaling: simplicity in design, versatility in function

(2011) E. R. Andersson et al.   DEVELOPMENT

Gene Regulation by MAPK Substrate Competition

(2011) Yoosik Kim et al.   DEVELOPMENTAL CELL

Roles of Drosophila Deltex in Notch receptor endocytic trafficking and activation

(2011) Kenta Yamada et al.   GENES TO CELLS

Notch signaling and Notch signaling modifiers

(2011) Michael M. Wang   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Activation Dynamics and Signaling Properties of Notch3 Receptor in the Developing Pulmonary Artery

(2011) Shamik Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Queueing up for enzymatic processing: correlated signaling through coupled degradation

(2011) N. A. Cookson et al.   Molecular Systems Biology

Delta1 Expression, Cell Cycle Exit, and Commitment to a Specific Secretory Fate Coincide within a Few Hours in the Mouse Intestinal Stem Cell System

(2011) Despina Stamataki et al.   PLoS One

A dynamical model of ommatidial crystal formation

(2011) D. K. Lubensky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction Between Notch and Hif-  in Development and Survival of Drosophila Blood Cells

(2011) T. Mukherjee et al.   SCIENCE

Mutual Inactivation of Notch Receptors and Ligands Facilitates Developmental Patterning

(2011) David Sprinzak et al.   PLoS Computational Biology

MAPK Substrate Competition Integrates Patterning Signals in the Drosophila Embryo

(2010) Yoosik Kim et al.   CURRENT BIOLOGY

A Role of Receptor Notch in Ligand cis-Inhibition in Drosophila

(2010) Isabelle Becam et al.   CURRENT BIOLOGY

Mechanisms of ligand-mediated inhibition in Notch signaling activity inDrosophila

(2010) Ulla-Maj Fiuza et al.   DEVELOPMENTAL DYNAMICS

The Notch signaling pathway: Molecular basis of cell context dependency

(2010) Ralf Schwanbeck et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The importance of structured noise in the generation of self-organizing tissue patterns through contact-mediated cell-cell signalling

(2010) M. Cohen et al.   Journal of the Royal Society Interface

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

Error Minimization in Lateral Inhibition Circuits

(2010) O. Barad et al.   Science Signaling

Delivering the Lateral Inhibition Punchline: It's All About the Timing

(2010) J. D. Axelrod   Science Signaling

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Notch Signalling: Receptor cis-Inhibition To Achieve Directionality

(2009) David del Álamo et al.   CURRENT BIOLOGY

cis-Inhibition of Notch by Endogenous Delta Biases the Outcome of Lateral Inhibition

(2009) Adam C. Miller et al.   CURRENT BIOLOGY

Endocytic regulation of Notch signaling

(2009) Mark E Fortini et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Lunatic fringe promotes the lateral inhibition of neurogenesis

(2009) N. Nikolaou et al.   DEVELOPMENT

Notch Signaling: The Core Pathway and Its Posttranslational Regulation

(2009) Mark E. Fortini   DEVELOPMENTAL CELL

Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division

(2009) F. Coumailleau et al.   NATURE

Endocytic Regulation of Notch Signalling During Development

(2009) Maximilian Fürthauer et al.   TRAFFIC

Ligand-Independent Traffic of Notch Buffers Activated Armadillo in Drosophila

(2009) Phil G. T. Sanders et al.   PLOS BIOLOGY

Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue

(2008) M. Matsuda et al.   DEVELOPMENT

Drosophila HOPS and AP-3 Complex Genes Are Required for a Deltex-Regulated Activation of Notch in the Endosomal Trafficking Pathway

(2008) Marian Wilkin et al.   DEVELOPMENTAL CELL

Robustness analysis of cellular memory in an autoactivating positive feedback system

(2008) Zhang Cheng et al.   FEBS LETTERS

A competitive complex formation mechanism underlies trichome patterning on Arabidopsis leaves

(2008) Simona Digiuni et al.   Molecular Systems Biology

Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition

(2008) Ryoichiro Kageyama et al.   NATURE NEUROSCIENCE

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition

(2008) Jemima Cordle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multistable Decision Switches for Flexible Control of Epigenetic Differentiation

(2008) Raúl Guantes et al.   PLoS Computational Biology