Sirt1 Deletion Leads to Enhanced Inflammation and Aggravates Endotoxin-Induced Acute Kidney Injury

Enhanced Dendritic Cell Survival Attenuates Lipopolysaccharide-Induced Immunosuppression and Increases Resistance to Lethal Endotoxic Shock

(2014) E. L. Gautier et al.   JOURNAL OF IMMUNOLOGY

ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury

(2013) Shixuan Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging

(2013) Hung-Chun Chang et al.   CELL

Biomarkers in sepsis

(2013) Mervyn Singer   CURRENT OPINION IN PULMONARY MEDICINE

Human umbilical cord mesenchymal stem cells attenuate cisplatin-induced acute and chronic renal injury

(2013) Xiujuan Peng et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Paeoniflorin suppresses vascular damage and the expression of E-selectin and ICAM-1 in a mouse model of cutaneous Arthus reaction

(2013) Tao Chen et al.   EXPERIMENTAL DERMATOLOGY

Procalcitonin induced cytotoxicity and apoptosis in mesangial cells: implications for septic renal injury

(2013) Magali Araujo et al.   INFLAMMATION RESEARCH

Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule–specific knockout mouse models

(2013) Qingqing Wei et al.   KIDNEY INTERNATIONAL

The histone deacetylase, SIRT1, contributes to the resistance of young mice to ischemia/reperfusion-induced acute kidney injury

(2013) Hong Fan et al.   KIDNEY INTERNATIONAL

Netrin-1 regulates the inflammatory response of neutrophils and macrophages, and suppresses ischemic acute kidney injury by inhibiting COX-2-mediated PGE2 production

(2013) Punithavathi V. Ranganathan et al.   KIDNEY INTERNATIONAL

High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway

(2013) Rokhsana Mortuza et al.   PLoS One

Acute Kidney Injury in Patients with Sepsis and Septic Shock: Risk Factors and Clinical Outcomes

(2013) Sang Heon Suh et al.   YONSEI MEDICAL JOURNAL

Sepsis: Update in the Management

(2012) Ramesh Venkataraman et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Sirt1 protects against thrombomodulin down-regulation and lung coagulation after particulate matter exposure

(2012) Z. Wu et al.   BLOOD

STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma

(2012) Bing Tu et al.   CANCER LETTERS

Severity of sepsis-induced acute kidney injury in a novel mouse model is age dependent*

(2012) Bert Maddens et al.   CRITICAL CARE MEDICINE

SIRT1 – An Anti-Inflammatory Pathway at the Crossroads Between Metabolic Disease and Atherosclerosis

(2012) Stephan Winnik et al.   Current Vascular Pharmacology

SIRT of liver metastases: physiological and pathophysiological considerations

(2012) Christophe Van de Wiele et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

5,7-Dihydroxy-3,4,6-trimethoxyflavone inhibits intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 via the Akt and nuclear factor-κB-dependent pathway, leading to suppression of adhesion of monocytes and eosinophils to bronchial epithe

(2012) Jireh Jung et al.   IMMUNOLOGY

MicroRNA-217 Promotes Ethanol-induced Fat Accumulation in Hepatocytes by Down-regulating SIRT1

(2012) Huquan Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirt-1 Is Required for the Inhibition of Apoptosis and Inflammatory Responses in Human Tenocytes

(2012) Franziska Busch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NAD+-dependent Sirtuin 1 and 6 Proteins Coordinate a Switch from Glucose to Fatty Acid Oxidation during the Acute Inflammatory Response

(2012) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe multiple organ injury in HSF1 knockout mice induced by lipopolysaccharide is associated with an increase in neutrophil infiltration and surface expression of adhesion molecules

(2012) Shuhua Chen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of high endothelial postcapillary venules and selected adhesion molecules in periodontal diseases: a review

(2012) A. Kasprzak et al.   JOURNAL OF PERIODONTAL RESEARCH

Persistent inflammation and immunosuppression

(2012) Lori F. Gentile et al.   Journal of Trauma and Acute Care Surgery

Novel Assays for Detection of Urinary KIM-1 in Mouse Models of Kidney Injury

(2012) Venkata S. Sabbisetti et al.   TOXICOLOGICAL SCIENCES

IL-6/IL-6 receptor system and its role in physiological and pathological conditions

(2011) Masahiko Mihara et al.   CLINICAL SCIENCE

Restriction of Advanced Glycation End Products Improves Insulin Resistance in Human Type 2 Diabetes: Potential role of AGER1 and SIRT1

(2011) J. Uribarri et al.   DIABETES CARE

Sirtuin 1 in immune regulation and autoimmunity

(2011) Sinyi Kong et al.   IMMUNOLOGY AND CELL BIOLOGY

Cigarette smoke-induced autophagy is regulated by SIRT1–PARP-1-dependent mechanism: Implication in pathogenesis of COPD

(2010) Jae-woong Hwang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Sirt1 activation protects the mouse renal medulla from oxidative injury

(2010) Wenjuan He et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3

(2010) C. J. Greenhill et al.   JOURNAL OF IMMUNOLOGY

Sirtuins and Their Relevance to the Kidney

(2010) C.-M. Hao et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pathophysiology of septic acute kidney injury: What do we really know?

(2008) Li Wan et al.   CRITICAL CARE MEDICINE

Accumulation, activation, and survival of neutrophils in ulcerative colitis: regulation by locally produced factors in the colon and impact of steroid treatment

(2008) Maria Lampinen et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

AP214, an analogue of α-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality

(2008) K. Doi et al.   KIDNEY INTERNATIONAL