Distinct and Overlapping Functions of ptpn11 Genes in Zebrafish Development
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Title
Distinct and Overlapping Functions of ptpn11 Genes in Zebrafish Development
Authors
Keywords
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Journal
PLoS One
Volume 9, Issue 4, Pages e94884
Publisher
Public Library of Science (PLoS)
Online
2014-04-16
DOI
10.1371/journal.pone.0094884
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Note: Only part of the references are listed.- Deletion of SHP-2 in mesenchymal stem cells causes growth retardation, limb and chest deformity, and calvarial defects in mice
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- Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature
- (2012) A. D. R. Serra-Nedelec et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis
- (2011) Emilie A. Bard-Chapeau et al. CANCER CELL
- Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome–associated PTPN11 mutation
- (2011) Talita M. Marin et al. JOURNAL OF CLINICAL INVESTIGATION
- Phosphatase-Dependent and -Independent Functions of Shp2 in Neural Crest Cells Underlie LEOPARD Syndrome Pathogenesis
- (2010) Rodney A. Stewart et al. DEVELOPMENTAL CELL
- Development of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutations
- (2010) T. J. Bauler et al. Disease Models & Mechanisms
- Functional Effects of PTPN11 (SHP2) Mutations Causing LEOPARD Syndrome on Epidermal Growth Factor-Induced Phosphoinositide 3-Kinase/AKT/Glycogen Synthase Kinase 3 Signaling
- (2010) T. Edouard et al. MOLECULAR AND CELLULAR BIOLOGY
- Identification and Expression of the Family of Classical Protein-Tyrosine Phosphatases in Zebrafish
- (2010) Mark van Eekelen et al. PLoS One
- Protein tyrosine phosphatase activity in the neural crest is essential for normal heart and skull development
- (2009) T. Nakamura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Noonan syndrome is associated with enhanced pERK activity, the repression of which can prevent craniofacial malformations
- (2009) T. Nakamura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of Ptpn11 (Shp2) in Cardiomyocytes Causes Dilated Cardiomyopathy via Effects on the Extracellular Signal–Regulated Kinase/Mitogen-Activated Protein Kinase and RhoA Signaling Pathways
- (2008) Maria I. Kontaridis et al. CIRCULATION
- Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development
- (2008) Kimihiko Oishi et al. HUMAN MOLECULAR GENETICS
- The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway
- (2007) Marie Dance et al. CELLULAR SIGNALLING
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