Gene Silencing of SOCS3 by siRNA Intranasal Delivery Inhibits Asthma Phenotype in Mice

An IL-4/IL-13 Dual Antagonist Reduces Lung Inflammation, Airway Hyperresponsiveness, and IgE Production in Mice

(2013) Marion T. Kasaian et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Innate and adaptive immune responses in asthma

(2012) Stephen T Holgate   NATURE MEDICINE

SOCS, Inflammation, and Autoimmunity

(2012) Akihiko Yoshimura et al.   Frontiers in Immunology

Intra-airway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuates allergic asthma in mice

(2011) Shintaro Miyamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Suppressors of Cytokine Signaling 3 Expression in Eosinophils: Regulation by PGE2and Th2 Cytokines

(2011) Esther López et al.   Clinical & Developmental Immunology

Role of Rho kinase isoforms in murine allergic airway responses

(2011) M. Zhu et al.   EUROPEAN RESPIRATORY JOURNAL

MicroRNAs Profiling in Murine Models of Acute and Chronic Asthma: A Relationship with mRNAs Targets

(2011) Nancy Garbacki et al.   PLoS One

Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic target

(2011) Adam Collison et al.   BMC Pulmonary Medicine

T Cell Treatment with Small Interfering RNA for Suppressor of Cytokine Signaling 3 Modulates Allergic Airway Responses in a Murine Model of Asthma

(2010) Atsushi Moriwaki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

RhoA, a Possible Target for Treatment of Airway Hyperresponsiveness in Bronchial Asthma

(2010) Yoshihiko Chiba et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

(2010) J. DeVincenzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rho Kinase (ROCK) Inhibitors and Their Application to Inflammatory Disorders

(2009) Philip LoGrasso et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Noninvasive Quantitative Tomography of the Therapeutic Response to Dexamethasone in Ovalbumin-Induced Murine Asthma

(2009) H. Korideck et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis

(2009) P Bonifazi et al.   Mucosal Immunology

Interleukin-4 upregulates RhoA protein via an activation of STAT6 in cultured human bronchial smooth muscle cells

(2009) Yoshihiko Chiba et al.   PHARMACOLOGICAL RESEARCH

The proximal STAT6 and NF-κB sites are responsible for IL-13- and TNF-α-induced RhoA transcriptions in human bronchial smooth muscle cells

(2009) Kumiko Goto et al.   PHARMACOLOGICAL RESEARCH

IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

(2008) Hidefumi Wakashin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interleukin-13 Augments Bronchial Smooth Muscle Contractility with an Up-Regulation of RhoA Protein

(2008) Yoshihiko Chiba et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Suppressor of cytokine signaling 1 inhibits IFN-γ inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation

(2008) Stefania Madonna et al.   FASEB JOURNAL